Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | GNF2_CASP4 |
| Enrichment Score (ES) | -0.6922755 |
| Normalized Enrichment Score (NES) | -1.7334764 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07870476 |
| FWER p-Value | 0.253 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | GMFG | NA | GMFG Entrez, Source | glia maturation factor, gamma | 4153 | 0.945 | -0.1201 | No |
| 2 | ZFP36L2 | NA | ZFP36L2 Entrez, Source | zinc finger protein 36, C3H type-like 2 | 5144 | 0.709 | -0.1323 | No |
| 3 | B2M | NA | B2M Entrez, Source | beta-2-microglobulin | 6491 | 0.454 | -0.1662 | No |
| 4 | DAZAP2 | NA | DAZAP2 Entrez, Source | DAZ associated protein 2 | 8574 | 0.258 | -0.2337 | No |
| 5 | ARPC3 | NA | ARPC3 Entrez, Source | actin related protein 2/3 complex, subunit 3, 21kDa | 8966 | 0.232 | -0.2401 | No |
| 6 | CMTM6 | NA | CMTM6 Entrez, Source | CKLF-like MARVEL transmembrane domain containing 6 | 10920 | 0.136 | -0.3070 | No |
| 7 | WAS | NA | WAS Entrez, Source | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 13022 | 0.052 | -0.3822 | No |
| 8 | ZCCHC6 | NA | ZCCHC6 Entrez, Source | zinc finger, CCHC domain containing 6 | 14810 | -0.013 | -0.4472 | No |
| 9 | ACTR2 | NA | ACTR2 Entrez, Source | ARP2 actin-related protein 2 homolog (yeast) | 18307 | -0.173 | -0.5694 | No |
| 10 | LAPTM5 | NA | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 18352 | -0.175 | -0.5651 | No |
| 11 | HCLS1 | NA | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 18598 | -0.193 | -0.5675 | No |
| 12 | PSTPIP1 | NA | PSTPIP1 Entrez, Source | proline-serine-threonine phosphatase interacting protein 1 | 19334 | -0.254 | -0.5858 | No |
| 13 | SH3BGRL3 | NA | SH3BGRL3 Entrez, Source | SH3 domain binding glutamic acid-rich protein like 3 | 19779 | -0.297 | -0.5920 | No |
| 14 | SELL | NA | SELL Entrez, Source | selectin L (lymphocyte adhesion molecule 1) | 21687 | -0.568 | -0.6426 | No |
| 15 | IQGAP1 | NA | IQGAP1 Entrez, Source | IQ motif containing GTPase activating protein 1 | 22330 | -0.693 | -0.6426 | No |
| 16 | GMIP | NA | GMIP Entrez, Source | GEM interacting protein | 23688 | -1.003 | -0.6583 | Yes |
| 17 | RIN3 | NA | RIN3 Entrez, Source | Ras and Rab interactor 3 | 23971 | -1.081 | -0.6319 | Yes |
| 18 | HSD17B11 | NA | 25014 | -1.423 | -0.6219 | Yes | ||
| 19 | HLA-B | NA | HLA-B Entrez, Source | major histocompatibility complex, class I, B | 26685 | -2.482 | -0.5989 | Yes |
| 20 | TCIRG1 | NA | TCIRG1 Entrez, Source | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 26835 | -2.712 | -0.5124 | Yes |
| 21 | ELF4 | NA | ELF4 Entrez, Source | E74-like factor 4 (ets domain transcription factor) | 26906 | -2.819 | -0.4194 | Yes |
| 22 | CASP4 | NA | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 27208 | -3.856 | -0.2997 | Yes |
| 23 | ICAM3 | NA | ICAM3 Entrez, Source | intercellular adhesion molecule 3 | 27285 | -4.456 | -0.1514 | Yes |
| 24 | STAT6 | NA | STAT6 Entrez, Source | signal transducer and activator of transcription 6, interleukin-4 induced | 27292 | -4.512 | 0.0014 | Yes |
