Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | GNF2_LYN |
| Enrichment Score (ES) | -0.62335455 |
| Normalized Enrichment Score (NES) | -1.8012571 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.052488312 |
| FWER p-Value | 0.129 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ERP29 | NA | ERP29 Entrez, Source | endoplasmic reticulum protein 29 | 2368 | 1.566 | -0.0352 | No |
| 2 | GIT2 | NA | GIT2 Entrez, Source | G protein-coupled receptor kinase interactor 2 | 2662 | 1.439 | 0.0014 | No |
| 3 | KIAA1033 | NA | KIAA1033 Entrez, Source | KIAA1033 | 3506 | 1.153 | 0.0085 | No |
| 4 | SKAP2 | NA | SKAP2 Entrez, Source | src kinase associated phosphoprotein 2 | 3810 | 1.047 | 0.0318 | No |
| 5 | HLA-DRA | NA | HLA-DRA Entrez, Source | major histocompatibility complex, class II, DR alpha | 6472 | 0.456 | -0.0506 | No |
| 6 | HLA-DMA | NA | HLA-DMA Entrez, Source | major histocompatibility complex, class II, DM alpha | 7272 | 0.369 | -0.0678 | No |
| 7 | DAZAP2 | NA | DAZAP2 Entrez, Source | DAZ associated protein 2 | 8574 | 0.258 | -0.1069 | No |
| 8 | HLA-DRB1 | NA | HLA-DRB1 Entrez, Source | major histocompatibility complex, class II, DR beta 1 | 8652 | 0.252 | -0.1015 | No |
| 9 | ARPC3 | NA | ARPC3 Entrez, Source | actin related protein 2/3 complex, subunit 3, 21kDa | 8966 | 0.232 | -0.1053 | No |
| 10 | CMTM6 | NA | CMTM6 Entrez, Source | CKLF-like MARVEL transmembrane domain containing 6 | 10920 | 0.136 | -0.1723 | No |
| 11 | WAS | NA | WAS Entrez, Source | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 13022 | 0.052 | -0.2476 | No |
| 12 | LAT2 | NA | LAT2 Entrez, Source | linker for activation of T cells family, member 2 | 13288 | 0.042 | -0.2559 | No |
| 13 | SYK | NA | SYK Entrez, Source | spleen tyrosine kinase | 14082 | 0.012 | -0.2846 | No |
| 14 | PTPN6 | NA | PTPN6 Entrez, Source | protein tyrosine phosphatase, non-receptor type 6 | 16067 | -0.063 | -0.3552 | No |
| 15 | CYBA | NA | CYBA Entrez, Source | cytochrome b-245, alpha polypeptide | 17388 | -0.119 | -0.3996 | No |
| 16 | LAPTM5 | NA | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 18352 | -0.175 | -0.4291 | No |
| 17 | HLA-DMB | NA | HLA-DMB Entrez, Source | major histocompatibility complex, class II, DM beta | 21288 | -0.495 | -0.5203 | No |
| 18 | SELL | NA | SELL Entrez, Source | selectin L (lymphocyte adhesion molecule 1) | 21687 | -0.568 | -0.5162 | No |
| 19 | SERP1 | NA | SERP1 Entrez, Source | - | 22652 | -0.765 | -0.5263 | No |
| 20 | SNX2 | NA | SNX2 Entrez, Source | sorting nexin 2 | 25302 | -1.551 | -0.5723 | Yes |
| 21 | LTA4H | NA | LTA4H Entrez, Source | leukotriene A4 hydrolase | 25387 | -1.586 | -0.5232 | Yes |
| 22 | SP110 | NA | SP110 Entrez, Source | SP110 nuclear body protein | 26326 | -2.150 | -0.4868 | Yes |
| 23 | CNPY3 | NA | 26363 | -2.182 | -0.4163 | Yes | ||
| 24 | RNASET2 | NA | RNASET2 Entrez, Source | ribonuclease T2 | 26581 | -2.368 | -0.3464 | Yes |
| 25 | LYN | NA | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 27040 | -3.155 | -0.2593 | Yes |
| 26 | MYD88 | NA | MYD88 Entrez, Source | myeloid differentiation primary response gene (88) | 27181 | -3.688 | -0.1431 | Yes |
| 27 | STAT6 | NA | STAT6 Entrez, Source | signal transducer and activator of transcription 6, interleukin-4 induced | 27292 | -4.512 | 0.0014 | Yes |
