Datasetexpression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls
#wt_versus_radiation.mainSample.cls
#wt_versus_radiation_repos
PhenotypemainSample.cls#wt_versus_radiation_repos
Upregulated in class2
GeneSetGNF2_MYD88
Enrichment Score (ES)-0.5936676
Normalized Enrichment Score (NES)-1.7242388
Nominal p-value0.0
FDR q-value0.079020254
FWER p-Value0.269
Table: GSEA Results Summary



Fig 1: Enrichment plot: GNF2_MYD88   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1RGS2NARGS2
Entrez,  Source
regulator of G-protein signalling 2, 24kDa5612.7040.0212No
2TMEM127NATMEM127
Entrez,  Source
transmembrane protein 12720451.700-0.0068No
3C1orf38NAC1ORF38
Entrez,  Source
chromosome 1 open reading frame 3830971.278-0.0256No
4RAB8ANARAB8A
Entrez,  Source
RAB8A, member RAS oncogene family34501.168-0.0205No
5SKAP2NASKAP2
Entrez,  Source
src kinase associated phosphoprotein 238101.047-0.0174No
6PTPRENAPTPRE
Entrez,  Source
protein tyrosine phosphatase, receptor type, E41290.951-0.0144No
7FKBP15NA52080.692-0.0432No
8TNFRSF1BNATNFRSF1B
Entrez,  Source
tumor necrosis factor receptor superfamily, member 1B75120.343-0.1224No
9DAZAP2NADAZAP2
Entrez,  Source
DAZ associated protein 285740.258-0.1573No
10ARPC3NAARPC3
Entrez,  Source
actin related protein 2/3 complex, subunit 3, 21kDa89660.232-0.1680No
11MAN2B1NAMAN2B1
Entrez,  Source
mannosidase, alpha, class 2B, member 190440.227-0.1674No
12SH2B3NASH2B3
Entrez,  Source
SH2B adaptor protein 390690.226-0.1647No
13CORO1ANACORO1A
Entrez,  Source
coronin, actin binding protein, 1A90740.226-0.1614No
14TYROBPNATYROBP
Entrez,  Source
TYRO protein tyrosine kinase binding protein105770.152-0.2141No
15CMTM6NACMTM6
Entrez,  Source
CKLF-like MARVEL transmembrane domain containing 6109200.136-0.2246No
16PAK2NAPAK2
Entrez,  Source
p21 (CDKN1A)-activated kinase 2112080.122-0.2332No
17CECR1NACECR1
Entrez,  Source
cat eye syndrome chromosome region, candidate 1118400.096-0.2548No
18PYCARDNAPYCARD
Entrez,  Source
PYD and CARD domain containing120170.090-0.2599No
19LILRA6NALILRA6
Entrez,  Source
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6128980.057-0.2913No
20WASNAWAS
Entrez,  Source
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)130220.052-0.2950No
21RHOANARHOA
Entrez,  Source
ras homolog gene family, member A131790.046-0.3000No
22DOCK2NADOCK2
Entrez,  Source
dedicator of cytokinesis 2139960.015-0.3297No
23FCER1GNAFCER1G
Entrez,  Source
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide141280.011-0.3343No
24SELPLGNASELPLG
Entrez,  Source
selectin P ligand143420.003-0.3421No
25C20orf24NAC20ORF24
Entrez,  Source
chromosome 20 open reading frame 2415855-0.054-0.3967No
26CD53NACD53
Entrez,  Source
CD53 molecule16512-0.081-0.4195No
27CYTH4NA16767-0.092-0.4274No
28LILRB1NALILRB1
Entrez,  Source
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 116826-0.094-0.4281No
29CYBANACYBA
Entrez,  Source
cytochrome b-245, alpha polypeptide17388-0.119-0.4468No
30ACTR2NAACTR2
Entrez,  Source
ARP2 actin-related protein 2 homolog (yeast)18307-0.173-0.4778No
31HCLS1NAHCLS1
Entrez,  Source
hematopoietic cell-specific Lyn substrate 118598-0.193-0.4854No
32LST1NALST1
Entrez,  Source
leukocyte specific transcript 119299-0.251-0.5072No
33SH3BGRL3NASH3BGRL3
Entrez,  Source
SH3 domain binding glutamic acid-rich protein like 319779-0.297-0.5202No
34CAP1NACAP1
Entrez,  Source
CAP, adenylate cyclase-associated protein 1 (yeast)20201-0.341-0.5304No
35CYBBNACYBB
Entrez,  Source
cytochrome b-245, beta polypeptide (chronic granulomatous disease)20252-0.349-0.5268No
36ARPC5NAARPC5
Entrez,  Source
actin related protein 2/3 complex, subunit 5, 16kDa20291-0.354-0.5227No
37MX2NAMX2
Entrez,  Source
myxovirus (influenza virus) resistance 2 (mouse)21251-0.489-0.5503No
38SELLNASELL
Entrez,  Source
selectin L (lymphocyte adhesion molecule 1)21687-0.568-0.5575No
39IQGAP1NAIQGAP1
Entrez,  Source
IQ motif containing GTPase activating protein 122330-0.693-0.5703No
40LSP1NALSP1
Entrez,  Source
lymphocyte-specific protein 122875-0.812-0.5777No
41USP3NAUSP3
Entrez,  Source
ubiquitin specific peptidase 323247-0.891-0.5775No
42GMIPNAGMIP
Entrez,  Source
GEM interacting protein23688-1.003-0.5782Yes
43MCL1NAMCL1
Entrez,  Source
myeloid cell leukemia sequence 1 (BCL2-related)23722-1.013-0.5637Yes
44RIN3NARIN3
Entrez,  Source
Ras and Rab interactor 323971-1.081-0.5561Yes
45ITGB2NAITGB2
Entrez,  Source
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)24721-1.317-0.5632Yes
46ARPC1BNAARPC1B
Entrez,  Source
actin related protein 2/3 complex, subunit 1B, 41kDa25503-1.643-0.5664Yes
47RPS6KA1NARPS6KA1
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 125626-1.700-0.5446Yes
48PRKCDNAPRKCD
Entrez,  Source
protein kinase C, delta26327-2.150-0.5370Yes
49CNPY3NA26363-2.182-0.5045Yes
50RNASET2NARNASET2
Entrez,  Source
ribonuclease T226581-2.368-0.4759Yes
51PSMB10NAPSMB10
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 1026623-2.409-0.4401Yes
52HLA-BNAHLA-B
Entrez,  Source
major histocompatibility complex, class I, B26685-2.482-0.4039Yes
53TCIRG1NATCIRG1
Entrez,  Source
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A326835-2.712-0.3675Yes
54ELF4NAELF4
Entrez,  Source
E74-like factor 4 (ets domain transcription factor)26906-2.819-0.3264Yes
55CASP1NACASP1
Entrez,  Source
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)26974-2.959-0.2831Yes
56LYNNALYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog27040-3.155-0.2367Yes
57FMNL1NAFMNL1
Entrez,  Source
formin-like 127118-3.438-0.1864Yes
58MYD88NAMYD88
Entrez,  Source
myeloid differentiation primary response gene (88)27181-3.688-0.1316Yes
59OSTF1NAOSTF1
Entrez,  Source
osteoclast stimulating factor 127276-4.343-0.0679Yes
60STAT6NASTAT6
Entrez,  Source
signal transducer and activator of transcription 6, interleukin-4 induced27292-4.5120.0014Yes
Table: GSEA details [plain text format]



Fig 2: GNF2_MYD88   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: GNF2_MYD88: Random ES distribution   
Gene set null distribution of ES for GNF2_MYD88