Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | GNF2_RAB3A |
| Enrichment Score (ES) | 0.65621597 |
| Normalized Enrichment Score (NES) | 1.6745806 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.058117453 |
| FWER p-Value | 0.396 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | DPP6 | NA | DPP6 Entrez, Source | dipeptidyl-peptidase 6 | 111 | 3.449 | 0.0698 | Yes |
| 2 | SYT11 | NA | SYT11 Entrez, Source | synaptotagmin XI | 360 | 2.981 | 0.1246 | Yes |
| 3 | ARNT2 | NA | ARNT2 Entrez, Source | aryl-hydrocarbon receptor nuclear translocator 2 | 541 | 2.730 | 0.1765 | Yes |
| 4 | EHD3 | NA | EHD3 Entrez, Source | EH-domain containing 3 | 576 | 2.693 | 0.2330 | Yes |
| 5 | NDRG4 | NA | NDRG4 Entrez, Source | NDRG family member 4 | 655 | 2.618 | 0.2862 | Yes |
| 6 | SV2A | NA | SV2A Entrez, Source | synaptic vesicle glycoprotein 2A | 713 | 2.560 | 0.3389 | Yes |
| 7 | CAMK2N1 | NA | CAMK2N1 Entrez, Source | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 1064 | 2.270 | 0.3747 | Yes |
| 8 | KIF5C | NA | KIF5C Entrez, Source | kinesin family member 5C | 1092 | 2.248 | 0.4219 | Yes |
| 9 | TAGLN3 | NA | TAGLN3 Entrez, Source | transgelin 3 | 1188 | 2.185 | 0.4652 | Yes |
| 10 | GABBR2 | NA | GABBR2 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 2 | 1803 | 1.821 | 0.4818 | Yes |
| 11 | FAIM2 | NA | FAIM2 Entrez, Source | Fas apoptotic inhibitory molecule 2 | 1841 | 1.805 | 0.5191 | Yes |
| 12 | NRCAM | NA | NRCAM Entrez, Source | neuronal cell adhesion molecule | 2208 | 1.630 | 0.5406 | Yes |
| 13 | ARHGEF9 | NA | ARHGEF9 Entrez, Source | Cdc42 guanine nucleotide exchange factor (GEF) 9 | 2257 | 1.614 | 0.5734 | Yes |
| 14 | RAB6B | NA | RAB6B Entrez, Source | RAB6B, member RAS oncogene family | 2459 | 1.524 | 0.5987 | Yes |
| 15 | DNM1 | NA | DNM1 Entrez, Source | dynamin 1 | 2462 | 1.521 | 0.6312 | Yes |
| 16 | GAP43 | NA | GAP43 Entrez, Source | growth associated protein 43 | 2743 | 1.403 | 0.6510 | Yes |
| 17 | KCNQ2 | NA | KCNQ2 Entrez, Source | potassium voltage-gated channel, KQT-like subfamily, member 2 | 3310 | 1.211 | 0.6562 | Yes |
| 18 | RAB3A | NA | RAB3A Entrez, Source | RAB3A, member RAS oncogene family | 4088 | 0.962 | 0.6484 | No |
| 19 | GDI1 | NA | GDI1 Entrez, Source | GDP dissociation inhibitor 1 | 6751 | 0.424 | 0.5599 | No |
| 20 | RUNDC3A | NA | 7643 | 0.331 | 0.5343 | No | ||
| 21 | SH3GL2 | NA | SH3GL2 Entrez, Source | SH3-domain GRB2-like 2 | 8223 | 0.283 | 0.5192 | No |
| 22 | SULT4A1 | NA | SULT4A1 Entrez, Source | sulfotransferase family 4A, member 1 | 9698 | 0.193 | 0.4693 | No |
| 23 | GABBR1 | NA | GABBR1 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 1 | 12674 | 0.065 | 0.3617 | No |
| 24 | SYN1 | NA | SYN1 Entrez, Source | synapsin I | 13172 | 0.046 | 0.3445 | No |
| 25 | GRM3 | NA | GRM3 Entrez, Source | glutamate receptor, metabotropic 3 | 15804 | -0.052 | 0.2492 | No |
| 26 | SV2B | NA | SV2B Entrez, Source | synaptic vesicle glycoprotein 2B | 17293 | -0.115 | 0.1971 | No |
| 27 | RALYL | NA | 17456 | -0.122 | 0.1938 | No | ||
| 28 | RGS7 | NA | RGS7 Entrez, Source | regulator of G-protein signalling 7 | 17631 | -0.130 | 0.1903 | No |
| 29 | SLC12A5 | NA | SLC12A5 Entrez, Source | solute carrier family 12, (potassium-chloride transporter) member 5 | 19071 | -0.233 | 0.1425 | No |
| 30 | FXYD7 | NA | FXYD7 Entrez, Source | FXYD domain containing ion transport regulator 7 | 20263 | -0.350 | 0.1064 | No |
| 31 | RCAN2 | NA | 20320 | -0.358 | 0.1120 | No | ||
| 32 | VAMP2 | NA | VAMP2 Entrez, Source | vesicle-associated membrane protein 2 (synaptobrevin 2) | 21212 | -0.482 | 0.0897 | No |
| 33 | EPB41L1 | NA | EPB41L1 Entrez, Source | erythrocyte membrane protein band 4.1-like 1 | 21842 | -0.598 | 0.0795 | No |
| 34 | KIF3C | NA | KIF3C Entrez, Source | kinesin family member 3C | 22057 | -0.639 | 0.0853 | No |
| 35 | SNAP91 | NA | SNAP91 Entrez, Source | synaptosomal-associated protein, 91kDa homolog (mouse) | 24696 | -1.307 | 0.0166 | No |
| 36 | STXBP1 | NA | STXBP1 Entrez, Source | syntaxin binding protein 1 | 25687 | -1.735 | 0.0175 | No |
| 37 | SYT1 | NA | SYT1 Entrez, Source | synaptotagmin I | 26109 | -1.987 | 0.0447 | No |
