Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | GNF2_SELL |
| Enrichment Score (ES) | -0.6929705 |
| Normalized Enrichment Score (NES) | -1.7513486 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.073808834 |
| FWER p-Value | 0.224 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | GIT2 | NA | GIT2 Entrez, Source | G protein-coupled receptor kinase interactor 2 | 2662 | 1.439 | -0.0734 | No |
| 2 | C1orf38 | NA | C1ORF38 Entrez, Source | chromosome 1 open reading frame 38 | 3097 | 1.278 | -0.0678 | No |
| 3 | SKAP2 | NA | SKAP2 Entrez, Source | src kinase associated phosphoprotein 2 | 3810 | 1.047 | -0.0763 | No |
| 4 | GMFG | NA | GMFG Entrez, Source | glia maturation factor, gamma | 4153 | 0.945 | -0.0729 | No |
| 5 | B2M | NA | B2M Entrez, Source | beta-2-microglobulin | 6491 | 0.454 | -0.1509 | No |
| 6 | OSBPL8 | NA | OSBPL8 Entrez, Source | oxysterol binding protein-like 8 | 8418 | 0.269 | -0.2170 | No |
| 7 | DAZAP2 | NA | DAZAP2 Entrez, Source | DAZ associated protein 2 | 8574 | 0.258 | -0.2183 | No |
| 8 | ARPC3 | NA | ARPC3 Entrez, Source | actin related protein 2/3 complex, subunit 3, 21kDa | 8966 | 0.232 | -0.2288 | No |
| 9 | CORO1A | NA | CORO1A Entrez, Source | coronin, actin binding protein, 1A | 9074 | 0.226 | -0.2289 | No |
| 10 | CMTM6 | NA | CMTM6 Entrez, Source | CKLF-like MARVEL transmembrane domain containing 6 | 10920 | 0.136 | -0.2942 | No |
| 11 | PAK2 | NA | PAK2 Entrez, Source | p21 (CDKN1A)-activated kinase 2 | 11208 | 0.122 | -0.3027 | No |
| 12 | WAS | NA | WAS Entrez, Source | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 13022 | 0.052 | -0.3683 | No |
| 13 | JUNB | NA | JUNB Entrez, Source | jun B proto-oncogene | 13778 | 0.023 | -0.3955 | No |
| 14 | ACAP2 | NA | 13909 | 0.018 | -0.4000 | No | ||
| 15 | GPSM3 | NA | GPSM3 Entrez, Source | G-protein signalling modulator 3 (AGS3-like, C. elegans) | 15135 | -0.027 | -0.4445 | No |
| 16 | DPEP2 | NA | DPEP2 Entrez, Source | dipeptidase 2 | 15503 | -0.041 | -0.4572 | No |
| 17 | PTPN6 | NA | PTPN6 Entrez, Source | protein tyrosine phosphatase, non-receptor type 6 | 16067 | -0.063 | -0.4768 | No |
| 18 | CD53 | NA | CD53 Entrez, Source | CD53 molecule | 16512 | -0.081 | -0.4917 | No |
| 19 | CYTH4 | NA | 16767 | -0.092 | -0.4995 | No | ||
| 20 | LRCH4 | NA | LRCH4 Entrez, Source | leucine-rich repeats and calponin homology (CH) domain containing 4 | 16978 | -0.100 | -0.5055 | No |
| 21 | LRRFIP1 | NA | LRRFIP1 Entrez, Source | leucine rich repeat (in FLII) interacting protein 1 | 17386 | -0.119 | -0.5184 | No |
| 22 | TRIM38 | NA | TRIM38 Entrez, Source | tripartite motif-containing 38 | 17856 | -0.145 | -0.5332 | No |
| 23 | LAPTM5 | NA | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 18352 | -0.175 | -0.5484 | No |
| 24 | HCLS1 | NA | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 18598 | -0.193 | -0.5541 | No |
| 25 | MX2 | NA | MX2 Entrez, Source | myxovirus (influenza virus) resistance 2 (mouse) | 21251 | -0.489 | -0.6431 | No |
| 26 | SELL | NA | SELL Entrez, Source | selectin L (lymphocyte adhesion molecule 1) | 21687 | -0.568 | -0.6495 | No |
| 27 | LSP1 | NA | LSP1 Entrez, Source | lymphocyte-specific protein 1 | 22875 | -0.812 | -0.6793 | Yes |
| 28 | USP3 | NA | USP3 Entrez, Source | ubiquitin specific peptidase 3 | 23247 | -0.891 | -0.6779 | Yes |
| 29 | ARRB2 | NA | ARRB2 Entrez, Source | arrestin, beta 2 | 23323 | -0.906 | -0.6654 | Yes |
| 30 | FAM65B | NA | 23650 | -0.993 | -0.6607 | Yes | ||
| 31 | GMIP | NA | GMIP Entrez, Source | GEM interacting protein | 23688 | -1.003 | -0.6452 | Yes |
| 32 | MCL1 | NA | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 23722 | -1.013 | -0.6293 | Yes |
| 33 | ARHGDIB | NA | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 24415 | -1.214 | -0.6343 | Yes |
| 34 | HSD17B11 | NA | 25014 | -1.423 | -0.6323 | Yes | ||
| 35 | CNPY3 | NA | 26363 | -2.182 | -0.6450 | Yes | ||
| 36 | RNASET2 | NA | RNASET2 Entrez, Source | ribonuclease T2 | 26581 | -2.368 | -0.6131 | Yes |
| 37 | HLA-B | NA | HLA-B Entrez, Source | major histocompatibility complex, class I, B | 26685 | -2.482 | -0.5751 | Yes |
| 38 | TCIRG1 | NA | TCIRG1 Entrez, Source | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 26835 | -2.712 | -0.5349 | Yes |
| 39 | CASP1 | NA | CASP1 Entrez, Source | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 26974 | -2.959 | -0.4902 | Yes |
| 40 | LYN | NA | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 27040 | -3.155 | -0.4395 | Yes |
| 41 | EVI2B | NA | EVI2B Entrez, Source | ecotropic viral integration site 2B | 27063 | -3.219 | -0.3862 | Yes |
| 42 | FMNL1 | NA | FMNL1 Entrez, Source | formin-like 1 | 27118 | -3.438 | -0.3304 | Yes |
| 43 | FXYD5 | NA | FXYD5 Entrez, Source | FXYD domain containing ion transport regulator 5 | 27160 | -3.575 | -0.2717 | Yes |
| 44 | MYD88 | NA | MYD88 Entrez, Source | myeloid differentiation primary response gene (88) | 27181 | -3.688 | -0.2104 | Yes |
| 45 | CASP4 | NA | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 27208 | -3.856 | -0.1465 | Yes |
| 46 | ICAM3 | NA | ICAM3 Entrez, Source | intercellular adhesion molecule 3 | 27285 | -4.456 | -0.0743 | Yes |
| 47 | STAT6 | NA | STAT6 Entrez, Source | signal transducer and activator of transcription 6, interleukin-4 induced | 27292 | -4.512 | 0.0014 | Yes |
