Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | MODULE_288 |
| Enrichment Score (ES) | 0.47263038 |
| Normalized Enrichment Score (NES) | 2.0232732 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.004499312 |
| FWER p-Value | 0.008 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CXCR4 | NA | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 51 | 3.653 | 0.1947 | Yes |
| 2 | C3AR1 | NA | C3AR1 Entrez, Source | complement component 3a receptor 1 | 718 | 2.553 | 0.3076 | Yes |
| 3 | EDNRB | NA | EDNRB Entrez, Source | endothelin receptor type B | 1044 | 2.286 | 0.4187 | Yes |
| 4 | CCR1 | NA | CCR1 Entrez, Source | chemokine (C-C motif) receptor 1 | 2059 | 1.692 | 0.4726 | Yes |
| 5 | AGTR1 | NA | AGTR1 Entrez, Source | angiotensin II receptor, type 1 | 5129 | 0.713 | 0.3986 | No |
| 6 | GRPR | NA | GRPR Entrez, Source | gastrin-releasing peptide receptor | 5200 | 0.694 | 0.4333 | No |
| 7 | CXCR5 | NA | 8601 | 0.256 | 0.3225 | No | ||
| 8 | CXCL13 | NA | CXCL13 Entrez, Source | chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant) | 9427 | 0.207 | 0.3035 | No |
| 9 | FPR1 | NA | FPR1 Entrez, Source | formyl peptide receptor 1 | 9604 | 0.197 | 0.3076 | No |
| 10 | TSHR | NA | TSHR Entrez, Source | thyroid stimulating hormone receptor | 10137 | 0.173 | 0.2974 | No |
| 11 | TACR1 | NA | TACR1 Entrez, Source | tachykinin receptor 1 | 10198 | 0.170 | 0.3044 | No |
| 12 | NPY5R | NA | NPY5R Entrez, Source | neuropeptide Y receptor Y5 | 10484 | 0.156 | 0.3024 | No |
| 13 | CCR8 | NA | CCR8 Entrez, Source | chemokine (C-C motif) receptor 8 | 11969 | 0.091 | 0.2529 | No |
| 14 | AGTR2 | NA | AGTR2 Entrez, Source | angiotensin II receptor, type 2 | 12540 | 0.070 | 0.2358 | No |
| 15 | OPRD1 | NA | OPRD1 Entrez, Source | opioid receptor, delta 1 | 12824 | 0.060 | 0.2286 | No |
| 16 | CCR3 | NA | CCR3 Entrez, Source | chemokine (C-C motif) receptor 3 | 13040 | 0.051 | 0.2235 | No |
| 17 | TACR2 | NA | TACR2 Entrez, Source | tachykinin receptor 2 | 13473 | 0.034 | 0.2095 | No |
| 18 | CCR5 | NA | CCR5 Entrez, Source | chemokine (C-C motif) receptor 5 | 13865 | 0.020 | 0.1963 | No |
| 19 | OPRK1 | NA | OPRK1 Entrez, Source | opioid receptor, kappa 1 | 14020 | 0.014 | 0.1914 | No |
| 20 | CX3CR1 | NA | CX3CR1 Entrez, Source | chemokine (C-X3-C motif) receptor 1 | 14724 | -0.011 | 0.1662 | No |
| 21 | TACR3 | NA | TACR3 Entrez, Source | tachykinin receptor 3 | 14940 | -0.019 | 0.1593 | No |
| 22 | CCR6 | NA | CCR6 Entrez, Source | chemokine (C-C motif) receptor 6 | 15455 | -0.039 | 0.1426 | No |
| 23 | DARC | NA | DARC Entrez, Source | Duffy blood group, chemokine receptor | 15518 | -0.041 | 0.1425 | No |
| 24 | AVPR1A | NA | AVPR1A Entrez, Source | arginine vasopressin receptor 1A | 15785 | -0.051 | 0.1356 | No |
| 25 | CXCR6 | NA | CXCR6 Entrez, Source | chemokine (C-X-C motif) receptor 6 | 16380 | -0.076 | 0.1179 | No |
| 26 | CCR2 | NA | CCR2 Entrez, Source | chemokine (C-C motif) receptor 2 | 16547 | -0.083 | 0.1163 | No |
| 27 | BDKRB1 | NA | BDKRB1 Entrez, Source | bradykinin receptor B1 | 16675 | -0.088 | 0.1163 | No |
| 28 | FPR2 | NA | 17173 | -0.109 | 0.1040 | No | ||
| 29 | C5AR1 | NA | C5AR1 Entrez, Source | complement component 5a receptor 1 | 17675 | -0.133 | 0.0928 | No |
| 30 | EDNRA | NA | EDNRA Entrez, Source | endothelin receptor type A | 18830 | -0.212 | 0.0619 | No |
| 31 | GNRHR | NA | GNRHR Entrez, Source | gonadotropin-releasing hormone receptor | 18926 | -0.220 | 0.0703 | No |
| 32 | NPY1R | NA | NPY1R Entrez, Source | neuropeptide Y receptor Y1 | 20294 | -0.354 | 0.0392 | No |
| 33 | CCL13 | NA | CCL13 Entrez, Source | chemokine (C-C motif) ligand 13 | 20652 | -0.399 | 0.0476 | No |
| 34 | BDKRB2 | NA | BDKRB2 Entrez, Source | bradykinin receptor B2 | 21108 | -0.469 | 0.0562 | No |
| 35 | OXTR | NA | OXTR Entrez, Source | oxytocin receptor | 24892 | -1.376 | -0.0084 | No |
| 36 | ATP8A1 | NA | ATP8A1 Entrez, Source | ATPase, aminophospholipid transporter (APLT), Class I, type 8A, member 1 | 25833 | -1.814 | 0.0548 | No |
