Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | MODULE_385 |
| Enrichment Score (ES) | 0.74742043 |
| Normalized Enrichment Score (NES) | 1.8546071 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.02836872 |
| FWER p-Value | 0.078 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PTN | NA | PTN Entrez, Source | pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1) | 18 | 3.898 | 0.1250 | Yes |
| 2 | APP | NA | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 128 | 3.406 | 0.2308 | Yes |
| 3 | NCAN | NA | 804 | 2.467 | 0.2856 | Yes | ||
| 4 | FGFR1 | NA | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 828 | 2.448 | 0.3636 | Yes |
| 5 | LPL | NA | LPL Entrez, Source | lipoprotein lipase | 1059 | 2.272 | 0.4284 | Yes |
| 6 | THBS2 | NA | THBS2 Entrez, Source | thrombospondin 2 | 1132 | 2.224 | 0.4975 | Yes |
| 7 | MDK | NA | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 1375 | 2.057 | 0.5550 | Yes |
| 8 | THBS4 | NA | THBS4 Entrez, Source | thrombospondin 4 | 1900 | 1.776 | 0.5930 | Yes |
| 9 | APOE | NA | APOE Entrez, Source | apolipoprotein E | 1901 | 1.776 | 0.6503 | Yes |
| 10 | FN1 | NA | FN1 Entrez, Source | fibronectin 1 | 1984 | 1.734 | 0.7032 | Yes |
| 11 | FSTL1 | NA | FSTL1 Entrez, Source | follistatin-like 1 | 2211 | 1.629 | 0.7474 | Yes |
| 12 | TGFBR3 | NA | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 3477 | 1.162 | 0.7385 | No |
| 13 | HBEGF | NA | HBEGF Entrez, Source | heparin-binding EGF-like growth factor | 4667 | 0.821 | 0.7215 | No |
| 14 | LIPC | NA | LIPC Entrez, Source | lipase, hepatic | 7473 | 0.346 | 0.6299 | No |
| 15 | CCL7 | NA | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 10412 | 0.160 | 0.5274 | No |
| 16 | CXCL6 | NA | CXCL6 Entrez, Source | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 12156 | 0.084 | 0.4663 | No |
| 17 | APOB | NA | APOB Entrez, Source | apolipoprotein B (including Ag(x) antigen) | 13212 | 0.045 | 0.4291 | No |
| 18 | CCL23 | NA | CCL23 Entrez, Source | chemokine (C-C motif) ligand 23 | 14077 | 0.012 | 0.3979 | No |
| 19 | HRG | NA | HRG Entrez, Source | histidine-rich glycoprotein | 14436 | -0.000 | 0.3848 | No |
| 20 | PRG2 | NA | PRG2 Entrez, Source | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 14538 | -0.004 | 0.3812 | No |
| 21 | VTN | NA | VTN Entrez, Source | vitronectin | 15462 | -0.039 | 0.3486 | No |
| 22 | CCL8 | NA | CCL8 Entrez, Source | chemokine (C-C motif) ligand 8 | 15532 | -0.042 | 0.3475 | No |
| 23 | APOH | NA | APOH Entrez, Source | apolipoprotein H (beta-2-glycoprotein I) | 16916 | -0.098 | 0.3000 | No |
| 24 | ABP1 | NA | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 17387 | -0.119 | 0.2866 | No |
| 25 | SERPIND1 | NA | SERPIND1 Entrez, Source | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 17518 | -0.125 | 0.2858 | No |
| 26 | FGF9 | NA | FGF9 Entrez, Source | fibroblast growth factor 9 (glia-activating factor) | 18634 | -0.196 | 0.2513 | No |
| 27 | FGFBP1 | NA | FGFBP1 Entrez, Source | fibroblast growth factor binding protein 1 | 22505 | -0.732 | 0.1332 | No |
| 28 | LAMC2 | NA | LAMC2 Entrez, Source | laminin, gamma 2 | 24814 | -1.349 | 0.0921 | No |
