Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | MODULE_417 |
| Enrichment Score (ES) | -0.59270877 |
| Normalized Enrichment Score (NES) | -1.8778361 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.03396042 |
| FWER p-Value | 0.054 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PLA2G5 | NA | PLA2G5 Entrez, Source | phospholipase A2, group V | 1550 | 1.953 | 0.0406 | No |
| 2 | IGF1 | NA | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 4165 | 0.941 | -0.0082 | No |
| 3 | ALDH5A1 | NA | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 4715 | 0.806 | 0.0119 | No |
| 4 | PAFAH2 | NA | PAFAH2 Entrez, Source | platelet-activating factor acetylhydrolase 2, 40kDa | 4942 | 0.756 | 0.0413 | No |
| 5 | LIPC | NA | LIPC Entrez, Source | lipase, hepatic | 7473 | 0.346 | -0.0341 | No |
| 6 | ACOX2 | NA | ACOX2 Entrez, Source | acyl-Coenzyme A oxidase 2, branched chain | 11947 | 0.092 | -0.1933 | No |
| 7 | APOC2 | NA | APOC2 Entrez, Source | apolipoprotein C-II | 12121 | 0.086 | -0.1953 | No |
| 8 | PLA2G2A | NA | PLA2G2A Entrez, Source | phospholipase A2, group IIA (platelets, synovial fluid) | 14628 | -0.007 | -0.2868 | No |
| 9 | PLD1 | NA | PLD1 Entrez, Source | phospholipase D1, phosphatidylcholine-specific | 15064 | -0.024 | -0.3015 | No |
| 10 | APOC3 | NA | APOC3 Entrez, Source | apolipoprotein C-III | 15295 | -0.033 | -0.3083 | No |
| 11 | PNLIPRP2 | NA | PNLIPRP2 Entrez, Source | pancreatic lipase-related protein 2 | 16366 | -0.076 | -0.3437 | No |
| 12 | CLPS | NA | CLPS Entrez, Source | colipase, pancreatic | 17432 | -0.121 | -0.3767 | No |
| 13 | PNLIP | NA | PNLIP Entrez, Source | pancreatic lipase | 17535 | -0.126 | -0.3741 | No |
| 14 | PLA2G7 | NA | PLA2G7 Entrez, Source | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 18654 | -0.197 | -0.4052 | No |
| 15 | HMGCS2 | NA | HMGCS2 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) | 19144 | -0.239 | -0.4112 | No |
| 16 | BAAT | NA | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 19885 | -0.308 | -0.4230 | No |
| 17 | PLCD1 | NA | PLCD1 Entrez, Source | phospholipase C, delta 1 | 20640 | -0.398 | -0.4307 | No |
| 18 | HMGCS1 | NA | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 24131 | -1.129 | -0.5023 | Yes |
| 19 | PLCG2 | NA | PLCG2 Entrez, Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 26602 | -2.383 | -0.4739 | Yes |
| 20 | LIPA | NA | LIPA Entrez, Source | lipase A, lysosomal acid, cholesterol esterase (Wolman disease) | 27072 | -3.246 | -0.3293 | Yes |
| 21 | PRDX6 | NA | PRDX6 Entrez, Source | peroxiredoxin 6 | 27086 | -3.307 | -0.1649 | Yes |
| 22 | SLC27A2 | NA | SLC27A2 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 2 | 27135 | -3.486 | 0.0071 | Yes |
