Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | MODULE_59 |
| Enrichment Score (ES) | 0.4995162 |
| Normalized Enrichment Score (NES) | 1.6685674 |
| Nominal p-value | 0.007751938 |
| FDR q-value | 0.05979918 |
| FWER p-Value | 0.409 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RAPGEF4 | NA | RAPGEF4 Entrez, Source | Rap guanine nucleotide exchange factor (GEF) 4 | 125 | 3.409 | 0.1432 | Yes |
| 2 | C3AR1 | NA | C3AR1 Entrez, Source | complement component 3a receptor 1 | 718 | 2.553 | 0.2321 | Yes |
| 3 | ITPR2 | NA | ITPR2 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 2 | 726 | 2.544 | 0.3422 | Yes |
| 4 | OLIG2 | NA | OLIG2 Entrez, Source | oligodendrocyte lineage transcription factor 2 | 1045 | 2.286 | 0.4296 | Yes |
| 5 | CA12 | NA | CA12 Entrez, Source | carbonic anhydrase XII | 2034 | 1.706 | 0.4674 | Yes |
| 6 | HSPB3 | NA | HSPB3 Entrez, Source | heat shock 27kDa protein 3 | 2798 | 1.387 | 0.4995 | Yes |
| 7 | KCNA3 | NA | KCNA3 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 3 | 4429 | 0.877 | 0.4778 | No |
| 8 | MAPK11 | NA | MAPK11 Entrez, Source | mitogen-activated protein kinase 11 | 6042 | 0.520 | 0.4413 | No |
| 9 | GPR183 | NA | 8105 | 0.291 | 0.3784 | No | ||
| 10 | SI | NA | SI Entrez, Source | sucrase-isomaltase (alpha-glucosidase) | 8839 | 0.240 | 0.3619 | No |
| 11 | CYP2E1 | NA | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 10317 | 0.164 | 0.3150 | No |
| 12 | SSX5 | NA | SSX5 Entrez, Source | synovial sarcoma, X breakpoint 5 | 10453 | 0.158 | 0.3169 | No |
| 13 | FUT9 | NA | FUT9 Entrez, Source | fucosyltransferase 9 (alpha (1,3) fucosyltransferase) | 11574 | 0.108 | 0.2805 | No |
| 14 | IL4 | NA | IL4 Entrez, Source | interleukin 4 | 12003 | 0.090 | 0.2687 | No |
| 15 | SRY | NA | SRY Entrez, Source | sex determining region Y | 12493 | 0.071 | 0.2539 | No |
| 16 | TRPA1 | NA | TRPA1 Entrez, Source | transient receptor potential cation channel, subfamily A, member 1 | 13831 | 0.021 | 0.2058 | No |
| 17 | RPGRIP1 | NA | RPGRIP1 Entrez, Source | retinitis pigmentosa GTPase regulator interacting protein 1 | 15448 | -0.038 | 0.1483 | No |
| 18 | CASQ2 | NA | CASQ2 Entrez, Source | calsequestrin 2 (cardiac muscle) | 15808 | -0.052 | 0.1374 | No |
| 19 | MSTN | NA | 16334 | -0.075 | 0.1214 | No | ||
| 20 | PPFIA2 | NA | PPFIA2 Entrez, Source | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 | 16986 | -0.101 | 0.1020 | No |
| 21 | IL5RA | NA | IL5RA Entrez, Source | interleukin 5 receptor, alpha | 17007 | -0.102 | 0.1056 | No |
| 22 | SLC6A4 | NA | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 17580 | -0.128 | 0.0902 | No |
| 23 | HCG4 | NA | HCG4 Entrez, Source | HLA complex group 4 | 18124 | -0.160 | 0.0773 | No |
| 24 | MAGEA10 | NA | MAGEA10 Entrez, Source | melanoma antigen family A, 10 | 18708 | -0.202 | 0.0647 | No |
| 25 | BMP6 | NA | BMP6 Entrez, Source | bone morphogenetic protein 6 | 25012 | -1.421 | -0.1046 | No |
| 26 | THOC5 | NA | THOC5 Entrez, Source | THO complex 5 | 26337 | -2.158 | -0.0595 | No |
| 27 | NFKBIE | NA | NFKBIE Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 26392 | -2.210 | 0.0343 | No |
