Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | MODULE_76 |
| Enrichment Score (ES) | 0.45501035 |
| Normalized Enrichment Score (NES) | 1.7508274 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.04913363 |
| FWER p-Value | 0.234 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | FOS | NA | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 3 | 4.177 | 0.0541 | Yes |
| 2 | IL1RAP | NA | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 13 | 3.933 | 0.1048 | Yes |
| 3 | C5 | NA | C5 Entrez, Source | complement component 5 | 15 | 3.923 | 0.1557 | Yes |
| 4 | BCL6 | NA | BCL6 Entrez, Source | B-cell CLL/lymphoma 6 (zinc finger protein 51) | 45 | 3.695 | 0.2026 | Yes |
| 5 | CXCR4 | NA | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 51 | 3.653 | 0.2498 | Yes |
| 6 | NFATC4 | NA | NFATC4 Entrez, Source | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 78 | 3.543 | 0.2948 | Yes |
| 7 | PTX3 | NA | PTX3 Entrez, Source | pentraxin-related gene, rapidly induced by IL-1 beta | 227 | 3.226 | 0.3313 | Yes |
| 8 | C3AR1 | NA | C3AR1 Entrez, Source | complement component 3a receptor 1 | 718 | 2.553 | 0.3464 | Yes |
| 9 | ANXA1 | NA | ANXA1 Entrez, Source | annexin A1 | 1067 | 2.267 | 0.3631 | Yes |
| 10 | MGLL | NA | MGLL Entrez, Source | monoglyceride lipase | 1086 | 2.251 | 0.3917 | Yes |
| 11 | CX3CL1 | NA | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 1151 | 2.210 | 0.4180 | Yes |
| 12 | ADORA1 | NA | ADORA1 Entrez, Source | adenosine A1 receptor | 1490 | 1.984 | 0.4313 | Yes |
| 13 | FN1 | NA | FN1 Entrez, Source | fibronectin 1 | 1984 | 1.734 | 0.4358 | Yes |
| 14 | CCR1 | NA | CCR1 Entrez, Source | chemokine (C-C motif) receptor 1 | 2059 | 1.692 | 0.4550 | Yes |
| 15 | C4B | NA | C4B Entrez, Source | complement component 4B (Childo blood group) | 2959 | 1.325 | 0.4392 | No |
| 16 | TPST1 | NA | TPST1 Entrez, Source | tyrosylprotein sulfotransferase 1 | 3140 | 1.262 | 0.4490 | No |
| 17 | AGER | NA | AGER Entrez, Source | advanced glycosylation end product-specific receptor | 4213 | 0.928 | 0.4217 | No |
| 18 | CXCL14 | NA | CXCL14 Entrez, Source | chemokine (C-X-C motif) ligand 14 | 4987 | 0.746 | 0.4030 | No |
| 19 | CCL17 | NA | CCL17 Entrez, Source | chemokine (C-C motif) ligand 17 | 6161 | 0.503 | 0.3665 | No |
| 20 | TLR1 | NA | TLR1 Entrez, Source | toll-like receptor 1 | 6645 | 0.436 | 0.3544 | No |
| 21 | CXCL9 | NA | CXCL9 Entrez, Source | chemokine (C-X-C motif) ligand 9 | 6726 | 0.426 | 0.3570 | No |
| 22 | CD14 | NA | CD14 Entrez, Source | CD14 molecule | 7652 | 0.330 | 0.3274 | No |
| 23 | PTGS2 | NA | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 9159 | 0.221 | 0.2750 | No |
| 24 | CXCL13 | NA | CXCL13 Entrez, Source | chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant) | 9427 | 0.207 | 0.2678 | No |
| 25 | S100A12 | NA | S100A12 Entrez, Source | S100 calcium binding protein A12 | 9458 | 0.206 | 0.2694 | No |
| 26 | FPR1 | NA | FPR1 Entrez, Source | formyl peptide receptor 1 | 9604 | 0.197 | 0.2667 | No |
| 27 | CCL2 | NA | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 9704 | 0.193 | 0.2655 | No |
| 28 | CCL7 | NA | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 10412 | 0.160 | 0.2417 | No |
| 29 | CXCL10 | NA | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 10692 | 0.147 | 0.2333 | No |
| 30 | CCL4 | NA | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 10911 | 0.137 | 0.2271 | No |
| 31 | CCL19 | NA | CCL19 Entrez, Source | chemokine (C-C motif) ligand 19 | 11737 | 0.100 | 0.1981 | No |
| 32 | PTAFR | NA | PTAFR Entrez, Source | platelet-activating factor receptor | 11738 | 0.100 | 0.1994 | No |
| 33 | CXCL6 | NA | CXCL6 Entrez, Source | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 12156 | 0.084 | 0.1852 | No |
| 34 | CCL21 | NA | CCL21 Entrez, Source | chemokine (C-C motif) ligand 21 | 12242 | 0.081 | 0.1832 | No |
| 35 | ALOX15 | NA | ALOX15 Entrez, Source | arachidonate 15-lipoxygenase | 12260 | 0.080 | 0.1836 | No |
| 36 | CCL20 | NA | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 12374 | 0.076 | 0.1804 | No |
| 37 | CXCL11 | NA | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 12633 | 0.066 | 0.1718 | No |
| 38 | ALOX5AP | NA | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 12698 | 0.064 | 0.1703 | No |
| 39 | LY86 | NA | LY86 Entrez, Source | lymphocyte antigen 86 | 12992 | 0.053 | 0.1602 | No |
| 40 | CCR5 | NA | CCR5 Entrez, Source | chemokine (C-C motif) receptor 5 | 13865 | 0.020 | 0.1285 | No |
| 41 | CCL23 | NA | CCL23 Entrez, Source | chemokine (C-C motif) ligand 23 | 14077 | 0.012 | 0.1209 | No |
| 42 | LY75 | NA | LY75 Entrez, Source | lymphocyte antigen 75 | 14245 | 0.006 | 0.1148 | No |
| 43 | AIF1 | NA | AIF1 Entrez, Source | allograft inflammatory factor 1 | 14416 | 0.001 | 0.1086 | No |
| 44 | CCL8 | NA | CCL8 Entrez, Source | chemokine (C-C motif) ligand 8 | 15532 | -0.042 | 0.0682 | No |
| 45 | IL8 | NA | IL8 Entrez, Source | interleukin 8 | 15907 | -0.056 | 0.0552 | No |
| 46 | AOAH | NA | AOAH Entrez, Source | acyloxyacyl hydrolase (neutrophil) | 16347 | -0.075 | 0.0401 | No |
| 47 | CCL18 | NA | CCL18 Entrez, Source | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 16420 | -0.078 | 0.0385 | No |
| 48 | CCR2 | NA | CCR2 Entrez, Source | chemokine (C-C motif) receptor 2 | 16547 | -0.083 | 0.0349 | No |
| 49 | FPR2 | NA | 17173 | -0.109 | 0.0134 | No | ||
| 50 | CXCL12 | NA | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 17216 | -0.111 | 0.0133 | No |
| 51 | ORM1 | NA | ORM1 Entrez, Source | orosomucoid 1 | 17369 | -0.118 | 0.0093 | No |
| 52 | TLR2 | NA | TLR2 Entrez, Source | toll-like receptor 2 | 17512 | -0.125 | 0.0057 | No |
| 53 | IL9 | NA | IL9 Entrez, Source | interleukin 9 | 18039 | -0.155 | -0.0116 | No |
| 54 | ALOX5 | NA | ALOX5 Entrez, Source | arachidonate 5-lipoxygenase | 18415 | -0.179 | -0.0231 | No |
| 55 | PLA2G7 | NA | PLA2G7 Entrez, Source | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 18654 | -0.197 | -0.0292 | No |
| 56 | CCL3 | NA | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 18961 | -0.223 | -0.0376 | No |
| 57 | ADORA2A | NA | ADORA2A Entrez, Source | adenosine A2a receptor | 18962 | -0.223 | -0.0347 | No |
| 58 | S100A9 | NA | S100A9 Entrez, Source | S100 calcium binding protein A9 | 19218 | -0.246 | -0.0408 | No |
| 59 | SAA1 | NA | SAA1 Entrez, Source | serum amyloid A1 | 19376 | -0.258 | -0.0433 | No |
| 60 | CYBB | NA | CYBB Entrez, Source | cytochrome b-245, beta polypeptide (chronic granulomatous disease) | 20252 | -0.349 | -0.0708 | No |
| 61 | TIRAP | NA | TIRAP Entrez, Source | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 20334 | -0.360 | -0.0691 | No |
| 62 | CCL13 | NA | CCL13 Entrez, Source | chemokine (C-C motif) ligand 13 | 20652 | -0.399 | -0.0756 | No |
| 63 | ABCF1 | NA | ABCF1 Entrez, Source | ATP-binding cassette, sub-family F (GCN20), member 1 | 20706 | -0.407 | -0.0723 | No |
| 64 | C3 | NA | C3 Entrez, Source | complement component 3 | 20783 | -0.420 | -0.0696 | No |
| 65 | BDKRB2 | NA | BDKRB2 Entrez, Source | bradykinin receptor B2 | 21108 | -0.469 | -0.0754 | No |
| 66 | NFKB1 | NA | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 21956 | -0.621 | -0.0984 | No |
| 67 | CCL11 | NA | CCL11 Entrez, Source | chemokine (C-C motif) ligand 11 | 21975 | -0.625 | -0.0910 | No |
| 68 | IL1A | NA | IL1A Entrez, Source | interleukin 1, alpha | 22157 | -0.658 | -0.0891 | No |
| 69 | TLR3 | NA | TLR3 Entrez, Source | toll-like receptor 3 | 22174 | -0.661 | -0.0811 | No |
| 70 | AOC3 | NA | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 22222 | -0.669 | -0.0741 | No |
| 71 | IL1B | NA | IL1B Entrez, Source | interleukin 1, beta | 22830 | -0.802 | -0.0860 | No |
| 72 | CXCL2 | NA | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 24873 | -1.368 | -0.1431 | No |
| 73 | CEBPB | NA | CEBPB Entrez, Source | CCAAT/enhancer binding protein (C/EBP), beta | 25505 | -1.643 | -0.1450 | No |
| 74 | CXCL1 | NA | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 25823 | -1.806 | -0.1332 | No |
| 75 | AOX1 | NA | AOX1 Entrez, Source | aldehyde oxidase 1 | 25963 | -1.893 | -0.1137 | No |
| 76 | IL1R1 | NA | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 26964 | -2.933 | -0.1123 | No |
| 77 | NMI | NA | NMI Entrez, Source | N-myc (and STAT) interactor | 26969 | -2.946 | -0.0742 | No |
| 78 | CD40 | NA | CD40 Entrez, Source | CD40 molecule, TNF receptor superfamily member 5 | 26999 | -3.035 | -0.0359 | No |
| 79 | CXCL5 | NA | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 27183 | -3.696 | 0.0054 | No |
