Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | MORF_LCAT |
| Enrichment Score (ES) | 0.3789421 |
| Normalized Enrichment Score (NES) | 1.6864402 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0653571 |
| FWER p-Value | 0.363 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | KIF1A | NA | KIF1A Entrez, Source | kinesin family member 1A | 80 | 3.535 | 0.0298 | Yes |
| 2 | BAI3 | NA | BAI3 Entrez, Source | brain-specific angiogenesis inhibitor 3 | 154 | 3.346 | 0.0582 | Yes |
| 3 | DZIP1 | NA | DZIP1 Entrez, Source | DAZ interacting protein 1 | 182 | 3.296 | 0.0877 | Yes |
| 4 | SOX3 | NA | SOX3 Entrez, Source | SRY (sex determining region Y)-box 3 | 241 | 3.192 | 0.1152 | Yes |
| 5 | TRIM9 | NA | TRIM9 Entrez, Source | tripartite motif-containing 9 | 251 | 3.172 | 0.1443 | Yes |
| 6 | ASTN1 | NA | ASTN1 Entrez, Source | astrotactin 1 | 359 | 2.982 | 0.1680 | Yes |
| 7 | SYT11 | NA | SYT11 Entrez, Source | synaptotagmin XI | 360 | 2.981 | 0.1956 | Yes |
| 8 | MPHOSPH8 | NA | 508 | 2.785 | 0.2160 | Yes | ||
| 9 | RBM17 | NA | RBM17 Entrez, Source | RNA binding motif protein 17 | 610 | 2.667 | 0.2370 | Yes |
| 10 | NACAD | NA | 725 | 2.545 | 0.2564 | Yes | ||
| 11 | TEKT2 | NA | TEKT2 Entrez, Source | tektin 2 (testicular) | 792 | 2.479 | 0.2770 | Yes |
| 12 | TRPC3 | NA | TRPC3 Entrez, Source | transient receptor potential cation channel, subfamily C, member 3 | 805 | 2.466 | 0.2994 | Yes |
| 13 | ART3 | NA | ART3 Entrez, Source | ADP-ribosyltransferase 3 | 1106 | 2.240 | 0.3091 | Yes |
| 14 | C1orf21 | NA | C1ORF21 Entrez, Source | chromosome 1 open reading frame 21 | 1127 | 2.227 | 0.3291 | Yes |
| 15 | VPS41 | NA | VPS41 Entrez, Source | vacuolar protein sorting 41 (yeast) | 1427 | 2.018 | 0.3368 | Yes |
| 16 | MYH7 | NA | MYH7 Entrez, Source | myosin, heavy chain 7, cardiac muscle, beta | 1433 | 2.014 | 0.3553 | Yes |
| 17 | HOXD9 | NA | HOXD9 Entrez, Source | homeobox D9 | 1561 | 1.945 | 0.3686 | Yes |
| 18 | OPHN1 | NA | OPHN1 Entrez, Source | oligophrenin 1 | 2041 | 1.702 | 0.3668 | Yes |
| 19 | IFT88 | NA | IFT88 Entrez, Source | intraflagellar transport 88 homolog (Chlamydomonas) | 2131 | 1.664 | 0.3789 | Yes |
| 20 | LRRTM2 | NA | LRRTM2 Entrez, Source | leucine rich repeat transmembrane neuronal 2 | 3374 | 1.192 | 0.3443 | No |
| 21 | STARD13 | NA | STARD13 Entrez, Source | START domain containing 13 | 3605 | 1.113 | 0.3462 | No |
| 22 | ODF2 | NA | ODF2 Entrez, Source | outer dense fiber of sperm tails 2 | 4045 | 0.974 | 0.3391 | No |
| 23 | GRM8 | NA | GRM8 Entrez, Source | glutamate receptor, metabotropic 8 | 4367 | 0.891 | 0.3355 | No |
| 24 | CXorf1 | NA | CXORF1 Entrez, Source | chromosome X open reading frame 1 | 4389 | 0.885 | 0.3430 | No |
| 25 | KCNA3 | NA | KCNA3 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 3 | 4429 | 0.877 | 0.3497 | No |
| 26 | PDCL | NA | PDCL Entrez, Source | phosducin-like | 4577 | 0.845 | 0.3521 | No |
| 27 | HIPK2 | NA | HIPK2 Entrez, Source | homeodomain interacting protein kinase 2 | 4804 | 0.788 | 0.3511 | No |
| 28 | C18orf25 | NA | C18ORF25 Entrez, Source | chromosome 18 open reading frame 25 | 4913 | 0.764 | 0.3542 | No |
| 29 | SCN2A | NA | 5072 | 0.728 | 0.3551 | No | ||
| 30 | SPAG8 | NA | SPAG8 Entrez, Source | sperm associated antigen 8 | 5096 | 0.721 | 0.3610 | No |
| 31 | TNNI2 | NA | TNNI2 Entrez, Source | troponin I type 2 (skeletal, fast) | 5277 | 0.669 | 0.3606 | No |
| 32 | SLCO2A1 | NA | SLCO2A1 Entrez, Source | solute carrier organic anion transporter family, member 2A1 | 5343 | 0.651 | 0.3642 | No |
| 33 | ZNF264 | NA | ZNF264 Entrez, Source | zinc finger protein 264 | 5395 | 0.640 | 0.3683 | No |
| 34 | EIF2B1 | NA | EIF2B1 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | 5507 | 0.616 | 0.3699 | No |
| 35 | RPGRIP1L | NA | 5584 | 0.599 | 0.3727 | No | ||
| 36 | SLC16A2 | NA | SLC16A2 Entrez, Source | solute carrier family 16, member 2 (monocarboxylic acid transporter 8) | 5747 | 0.571 | 0.3720 | No |
| 37 | SEC14L2 | NA | SEC14L2 Entrez, Source | SEC14-like 2 (S. cerevisiae) | 5882 | 0.550 | 0.3722 | No |
| 38 | ATRNL1 | NA | ATRNL1 Entrez, Source | attractin-like 1 | 7986 | 0.302 | 0.2977 | No |
| 39 | HDAC9 | NA | HDAC9 Entrez, Source | histone deacetylase 9 | 8162 | 0.287 | 0.2939 | No |
| 40 | PRM2 | NA | PRM2 Entrez, Source | protamine 2 | 8277 | 0.279 | 0.2923 | No |
| 41 | ZFY | NA | ZFY Entrez, Source | zinc finger protein, Y-linked | 8605 | 0.256 | 0.2826 | No |
| 42 | FOXN2 | NA | FOXN2 Entrez, Source | forkhead box N2 | 8618 | 0.255 | 0.2846 | No |
| 43 | LCT | NA | LCT Entrez, Source | lactase | 8904 | 0.236 | 0.2763 | No |
| 44 | CHRNA3 | NA | CHRNA3 Entrez, Source | cholinergic receptor, nicotinic, alpha 3 | 9167 | 0.221 | 0.2687 | No |
| 45 | PHKG2 | NA | PHKG2 Entrez, Source | phosphorylase kinase, gamma 2 (testis) | 9226 | 0.218 | 0.2686 | No |
| 46 | MYBPH | NA | MYBPH Entrez, Source | myosin binding protein H | 9432 | 0.207 | 0.2629 | No |
| 47 | CD3G | NA | CD3G Entrez, Source | CD3g molecule, gamma (CD3-TCR complex) | 9551 | 0.201 | 0.2605 | No |
| 48 | BMPER | NA | BMPER Entrez, Source | BMP binding endothelial regulator | 9849 | 0.186 | 0.2513 | No |
| 49 | EPHA7 | NA | EPHA7 Entrez, Source | EPH receptor A7 | 9981 | 0.179 | 0.2481 | No |
| 50 | SPAM1 | NA | SPAM1 Entrez, Source | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) | 10212 | 0.169 | 0.2412 | No |
| 51 | AKAP4 | NA | AKAP4 Entrez, Source | A kinase (PRKA) anchor protein 4 | 10239 | 0.168 | 0.2418 | No |
| 52 | OPN1SW | NA | OPN1SW Entrez, Source | opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) | 10267 | 0.166 | 0.2424 | No |
| 53 | DCC | NA | DCC Entrez, Source | deleted in colorectal carcinoma | 10366 | 0.162 | 0.2403 | No |
| 54 | TPH1 | NA | TPH1 Entrez, Source | tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) | 10458 | 0.158 | 0.2384 | No |
| 55 | NPY5R | NA | NPY5R Entrez, Source | neuropeptide Y receptor Y5 | 10484 | 0.156 | 0.2389 | No |
| 56 | TNNT2 | NA | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 10748 | 0.144 | 0.2306 | No |
| 57 | FSTL4 | NA | FSTL4 Entrez, Source | follistatin-like 4 | 10888 | 0.138 | 0.2267 | No |
| 58 | GPR4 | NA | GPR4 Entrez, Source | G protein-coupled receptor 4 | 11084 | 0.128 | 0.2208 | No |
| 59 | ZNF208 | NA | ZNF208 Entrez, Source | zinc finger protein 208 | 11260 | 0.120 | 0.2154 | No |
| 60 | ELF5 | NA | ELF5 Entrez, Source | E74-like factor 5 (ets domain transcription factor) | 11300 | 0.118 | 0.2151 | No |
| 61 | CRP | NA | CRP Entrez, Source | C-reactive protein, pentraxin-related | 11308 | 0.117 | 0.2159 | No |
| 62 | UGT2B4 | NA | UGT2B4 Entrez, Source | UDP glucuronosyltransferase 2 family, polypeptide B4 | 11531 | 0.109 | 0.2088 | No |
| 63 | CCL19 | NA | CCL19 Entrez, Source | chemokine (C-C motif) ligand 19 | 11737 | 0.100 | 0.2022 | No |
| 64 | KIAA1024 | NA | KIAA1024 Entrez, Source | - | 11765 | 0.099 | 0.2021 | No |
| 65 | RFX1 | NA | RFX1 Entrez, Source | regulatory factor X, 1 (influences HLA class II expression) | 11826 | 0.097 | 0.2008 | No |
| 66 | ATG4B | NA | ATG4B Entrez, Source | ATG4 autophagy related 4 homolog B (S. cerevisiae) | 11869 | 0.095 | 0.2001 | No |
| 67 | WNT1 | NA | WNT1 Entrez, Source | wingless-type MMTV integration site family, member 1 | 11953 | 0.092 | 0.1979 | No |
| 68 | AVP | NA | AVP Entrez, Source | arginine vasopressin (neurophysin II, antidiuretic hormone, diabetes insipidus, neurohypophyseal) | 12409 | 0.075 | 0.1819 | No |
| 69 | C9 | NA | C9 Entrez, Source | complement component 9 | 12675 | 0.065 | 0.1728 | No |
| 70 | KRT37 | NA | KRT37 Entrez, Source | keratin 37 | 12896 | 0.057 | 0.1652 | No |
| 71 | BHMT | NA | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 12989 | 0.053 | 0.1623 | No |
| 72 | NMBR | NA | NMBR Entrez, Source | neuromedin B receptor | 13117 | 0.048 | 0.1581 | No |
| 73 | GLRB | NA | GLRB Entrez, Source | glycine receptor, beta | 13381 | 0.038 | 0.1488 | No |
| 74 | BRDT | NA | BRDT Entrez, Source | bromodomain, testis-specific | 13413 | 0.037 | 0.1480 | No |
| 75 | XPNPEP2 | NA | XPNPEP2 Entrez, Source | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound | 13674 | 0.027 | 0.1387 | No |
| 76 | CRYBB3 | NA | CRYBB3 Entrez, Source | crystallin, beta B3 | 13854 | 0.020 | 0.1323 | No |
| 77 | GPR44 | NA | GPR44 Entrez, Source | G protein-coupled receptor 44 | 14024 | 0.014 | 0.1262 | No |
| 78 | GRM7 | NA | GRM7 Entrez, Source | glutamate receptor, metabotropic 7 | 14274 | 0.005 | 0.1171 | No |
| 79 | SAA4 | NA | SAA4 Entrez, Source | serum amyloid A4, constitutive | 14328 | 0.003 | 0.1152 | No |
| 80 | HSD17B2 | NA | HSD17B2 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 2 | 14388 | 0.002 | 0.1130 | No |
| 81 | PDE6C | NA | PDE6C Entrez, Source | phosphodiesterase 6C, cGMP-specific, cone, alpha prime | 14454 | -0.001 | 0.1106 | No |
| 82 | ZNF154 | NA | ZNF154 Entrez, Source | zinc finger protein 154 | 14493 | -0.002 | 0.1092 | No |
| 83 | LCAT | NA | LCAT Entrez, Source | lecithin-cholesterol acyltransferase | 14780 | -0.012 | 0.0988 | No |
| 84 | DMP1 | NA | DMP1 Entrez, Source | dentin matrix acidic phosphoprotein | 14930 | -0.018 | 0.0935 | No |
| 85 | KCNH1 | NA | KCNH1 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 1 | 14996 | -0.021 | 0.0913 | No |
| 86 | GK2 | NA | GK2 Entrez, Source | glycerol kinase 2 | 15027 | -0.022 | 0.0904 | No |
| 87 | RPGRIP1 | NA | RPGRIP1 Entrez, Source | retinitis pigmentosa GTPase regulator interacting protein 1 | 15448 | -0.038 | 0.0754 | No |
| 88 | AVPR1A | NA | AVPR1A Entrez, Source | arginine vasopressin receptor 1A | 15785 | -0.051 | 0.0635 | No |
| 89 | IFNA4 | NA | IFNA4 Entrez, Source | interferon, alpha 4 | 16416 | -0.078 | 0.0410 | No |
| 90 | GIF | NA | GIF Entrez, Source | gastric intrinsic factor (vitamin B synthesis) | 16447 | -0.079 | 0.0407 | No |
| 91 | TNFSF11 | NA | TNFSF11 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 11 | 16461 | -0.079 | 0.0409 | No |
| 92 | GABRA6 | NA | GABRA6 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, alpha 6 | 16571 | -0.084 | 0.0377 | No |
| 93 | SOX12 | NA | SOX12 Entrez, Source | SRY (sex determining region Y)-box 12 | 17247 | -0.112 | 0.0139 | No |
| 94 | CUL3 | NA | CUL3 Entrez, Source | cullin 3 | 18027 | -0.155 | -0.0133 | No |
| 95 | IL9 | NA | IL9 Entrez, Source | interleukin 9 | 18039 | -0.155 | -0.0123 | No |
| 96 | VIPR2 | NA | VIPR2 Entrez, Source | vasoactive intestinal peptide receptor 2 | 18050 | -0.156 | -0.0112 | No |
| 97 | HCG4 | NA | HCG4 Entrez, Source | HLA complex group 4 | 18124 | -0.160 | -0.0124 | No |
| 98 | CYP1A2 | NA | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 18392 | -0.178 | -0.0206 | No |
| 99 | ANGPTL7 | NA | ANGPTL7 Entrez, Source | angiopoietin-like 7 | 18485 | -0.185 | -0.0222 | No |
| 100 | FAM13C | NA | 18971 | -0.224 | -0.0380 | No | ||
| 101 | FRK | NA | FRK Entrez, Source | fyn-related kinase | 19712 | -0.290 | -0.0625 | No |
| 102 | CST5 | NA | CST5 Entrez, Source | cystatin D | 19805 | -0.300 | -0.0631 | No |
| 103 | BAAT | NA | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 19885 | -0.308 | -0.0631 | No |
| 104 | MATN4 | NA | MATN4 Entrez, Source | matrilin 4 | 20423 | -0.371 | -0.0795 | No |
| 105 | IL18RAP | NA | IL18RAP Entrez, Source | interleukin 18 receptor accessory protein | 20475 | -0.377 | -0.0778 | No |
| 106 | DOHH | NA | DOHH Entrez, Source | deoxyhypusine hydroxylase/monooxygenase | 20484 | -0.378 | -0.0746 | No |
| 107 | AKR1D1 | NA | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 20543 | -0.386 | -0.0732 | No |
| 108 | ADAM7 | NA | ADAM7 Entrez, Source | ADAM metallopeptidase domain 7 | 20789 | -0.421 | -0.0783 | No |
| 109 | TCF21 | NA | TCF21 Entrez, Source | transcription factor 21 | 21020 | -0.456 | -0.0825 | No |
| 110 | KIAA0391 | NA | KIAA0391 Entrez, Source | KIAA0391 | 21361 | -0.508 | -0.0903 | No |
| 111 | AP4E1 | NA | AP4E1 Entrez, Source | adaptor-related protein complex 4, epsilon 1 subunit | 21644 | -0.560 | -0.0955 | No |
| 112 | SERPINC1 | NA | SERPINC1 Entrez, Source | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 21754 | -0.582 | -0.0941 | No |
| 113 | SLC2A4 | NA | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 22083 | -0.645 | -0.1002 | No |
| 114 | DOC2A | NA | DOC2A Entrez, Source | double C2-like domains, alpha | 22406 | -0.709 | -0.1054 | No |
| 115 | NEU3 | NA | NEU3 Entrez, Source | sialidase 3 (membrane sialidase) | 22517 | -0.733 | -0.1027 | No |
| 116 | GCNT2 | NA | GCNT2 Entrez, Source | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 23377 | -0.921 | -0.1257 | No |
| 117 | GPR176 | NA | GPR176 Entrez, Source | G protein-coupled receptor 176 | 24547 | -1.260 | -0.1570 | No |
| 118 | BTC | NA | BTC Entrez, Source | betacellulin | 24641 | -1.291 | -0.1485 | No |
| 119 | SSX2IP | NA | SSX2IP Entrez, Source | synovial sarcoma, X breakpoint 2 interacting protein | 24652 | -1.294 | -0.1369 | No |
| 120 | P2RY6 | NA | P2RY6 Entrez, Source | pyrimidinergic receptor P2Y, G-protein coupled, 6 | 25156 | -1.486 | -0.1416 | No |
| 121 | MLLT3 | NA | MLLT3 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 25226 | -1.511 | -0.1301 | No |
| 122 | ZNF239 | NA | ZNF239 Entrez, Source | zinc finger protein 239 | 25643 | -1.709 | -0.1296 | No |
| 123 | RASGRF1 | NA | RASGRF1 Entrez, Source | Ras protein-specific guanine nucleotide-releasing factor 1 | 25761 | -1.774 | -0.1174 | No |
| 124 | NLE1 | NA | NLE1 Entrez, Source | notchless homolog 1 (Drosophila) | 25839 | -1.817 | -0.1034 | No |
| 125 | COX10 | NA | COX10 Entrez, Source | COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) | 25950 | -1.884 | -0.0900 | No |
| 126 | MAP3K14 | NA | MAP3K14 Entrez, Source | mitogen-activated protein kinase kinase kinase 14 | 26113 | -1.991 | -0.0775 | No |
| 127 | SNUPN | NA | SNUPN Entrez, Source | snurportin 1 | 26170 | -2.042 | -0.0606 | No |
| 128 | DKFZP586K1520 | NA | DKFZP586K1520 Entrez, Source | - | 26425 | -2.233 | -0.0492 | No |
| 129 | MTRF1L | NA | MTRF1L Entrez, Source | mitochondrial translational release factor 1-like | 26699 | -2.503 | -0.0361 | No |
| 130 | DCAF4 | NA | 26909 | -2.821 | -0.0176 | No | ||
| 131 | TCF15 | NA | TCF15 Entrez, Source | transcription factor 15 (basic helix-loop-helix) | 27153 | -3.559 | 0.0065 | No |
