Datasetexpression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls
#wt_versus_radiation.mainSample.cls
#wt_versus_radiation_repos
PhenotypemainSample.cls#wt_versus_radiation_repos
Upregulated in class1
GeneSetBMI1_DN.V1_DN
Enrichment Score (ES)0.50474507
Normalized Enrichment Score (NES)1.6165402
Nominal p-value0.004115226
FDR q-value0.009091553
FWER p-Value0.081
Table: GSEA Results Summary



Fig 1: Enrichment plot: BMI1_DN.V1_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1FOSNAFOS
Entrez,  Source
v-fos FBJ murine osteosarcoma viral oncogene homolog34.1770.0218Yes
2COL9A3NACOL9A3
Entrez,  Source
collagen, type IX, alpha 3383.7300.0401Yes
3C1orf54NAC1ORF54
Entrez,  Source
chromosome 1 open reading frame 54853.5280.0569Yes
4SSBP2NASSBP2
Entrez,  Source
single-stranded DNA binding protein 21103.4500.0741Yes
5GPR162NAGPR162
Entrez,  Source
G protein-coupled receptor 1621203.4190.0917Yes
6PPARGC1ANAPPARGC1A
Entrez,  Source
peroxisome proliferative activated receptor, gamma, coactivator 1, alpha1363.3870.1089Yes
7PDE4BNAPDE4B
Entrez,  Source
phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)1473.3650.1262Yes
8DOK5NADOK5
Entrez,  Source
docking protein 51533.3460.1435Yes
9ID4NAID4
Entrez,  Source
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein1723.3040.1602Yes
10SSPNNASSPN
Entrez,  Source
sarcospan (Kras oncogene-associated gene)1803.2980.1772Yes
11PNMAL1NA2003.2720.1937Yes
12HOXB13NAHOXB13
Entrez,  Source
homeobox B132883.1030.2067Yes
13VAV3NAVAV3
Entrez,  Source
vav 3 oncogene3193.0470.2216Yes
14NDRG2NANDRG2
Entrez,  Source
NDRG family member 23203.0450.2376Yes
15IFI44LNAIFI44L
Entrez,  Source
interferon-induced protein 44-like3223.0450.2535Yes
16SOX2NASOX2
Entrez,  Source
SRY (sex determining region Y)-box 23423.0090.2686Yes
17CLIP3NA4212.9020.2809Yes
18METTL7ANAMETTL7A
Entrez,  Source
methyltransferase like 7A4332.8890.2956Yes
19EPHA4NAEPHA4
Entrez,  Source
EPH receptor A44592.8610.3097Yes
20SEPP1NASEPP1
Entrez,  Source
selenoprotein P, plasma, 14792.8300.3238Yes
21ETV1NAETV1
Entrez,  Source
ets variant gene 16152.6600.3328Yes
22GTF2INAGTF2I
Entrez,  Source
general transcription factor II, i6892.5870.3437Yes
23GAS2NAGAS2
Entrez,  Source
growth arrest-specific 28102.4650.3522Yes
24ARHGAP12NAARHGAP12
Entrez,  Source
Rho GTPase activating protein 128292.4470.3644Yes
25CTNNBIP1NACTNNBIP1
Entrez,  Source
catenin, beta interacting protein 18452.4370.3766Yes
26PEG3NAPEG3
Entrez,  Source
paternally expressed 38862.4000.3877Yes
27CITED1NACITED1
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 110022.3160.3956Yes
28CHL1NACHL1
Entrez,  Source
cell adhesion molecule with homology to L1CAM (close homolog of L1)13092.0950.3954Yes
29DCTN6NADCTN6
Entrez,  Source
dynactin 613782.0550.4036Yes
30BST2NABST2
Entrez,  Source
bone marrow stromal cell antigen 214302.0170.4123Yes
31KCNJ16NAKCNJ16
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 1614711.9950.4213Yes
32SH3BGRLNASH3BGRL
Entrez,  Source
SH3 domain binding glutamic acid-rich protein like15271.9620.4296Yes
33WFDC2NAWFDC2
Entrez,  Source
WAP four-disulfide core domain 216371.9020.4355Yes
34HS6ST1NAHS6ST1
Entrez,  Source
heparan sulfate 6-O-sulfotransferase 116581.8940.4447Yes
35CA2NACA2
Entrez,  Source
carbonic anhydrase II17351.8540.4517Yes
36PLEKHA4NAPLEKHA4
Entrez,  Source
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 417631.8430.4603Yes
37TRPS1NATRPS1
Entrez,  Source
trichorhinophalangeal syndrome I18901.7800.4650Yes
38HIST1H4HNAHIST1H4H
Entrez,  Source
histone cluster 1, H4h21331.6630.4648Yes
39EFHD1NAEFHD1
Entrez,  Source
EF-hand domain family, member D123761.5610.4641Yes
40TMEM176BNATMEM176B
Entrez,  Source
transmembrane protein 176B24981.5060.4676Yes
41PID1NA29131.3450.4594Yes
42HIST2H2BENAHIST2H2BE
Entrez,  Source
histone cluster 2, H2be29761.3180.4640Yes
43CREMNACREM
Entrez,  Source
cAMP responsive element modulator30431.2960.4684Yes
44PCDH8NAPCDH8
Entrez,  Source
protocadherin 831191.2690.4723Yes
45NENFNANENF
Entrez,  Source
neuron derived neurotrophic factor31841.2470.4765Yes
46GPX3NAGPX3
Entrez,  Source
glutathione peroxidase 3 (plasma)32781.2200.4794Yes
47DYNLT3NADYNLT3
Entrez,  Source
dynein, light chain, Tctex-type 332971.2150.4851Yes
48SNX4NASNX4
Entrez,  Source
sorting nexin 432981.2150.4915Yes
49ZNF423NAZNF423
Entrez,  Source
zinc finger protein 42334541.1670.4919Yes
50GAS7NAGAS7
Entrez,  Source
growth arrest-specific 735201.1480.4956Yes
51TRIM2NATRIM2
Entrez,  Source
tripartite motif-containing 238791.0240.4878Yes
52TRAPPC6ANATRAPPC6A
Entrez,  Source
trafficking protein particle complex 6A39251.0110.4914Yes
53NMNAT2NANMNAT2
Entrez,  Source
nicotinamide nucleotide adenylyltransferase 239311.0080.4965Yes
54COL4A3BPNACOL4A3BP
Entrez,  Source
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein40630.9690.4968Yes
55ETFBNAETFB
Entrez,  Source
electron-transfer-flavoprotein, beta polypeptide42020.9310.4966Yes
56IFITM1NAIFITM1
Entrez,  Source
interferon induced transmembrane protein 1 (9-27)43660.8910.4952Yes
57TMEM176ANATMEM176A
Entrez,  Source
transmembrane protein 176A43930.8840.4989Yes
58SEMA3ENASEMA3E
Entrez,  Source
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E45170.8570.4989Yes
59PRPHNAPRPH
Entrez,  Source
peripherin45470.8510.5023Yes
60PCP4NAPCP4
Entrez,  Source
Purkinje cell protein 446010.8420.5047Yes
61IDH1NAIDH1
Entrez,  Source
isocitrate dehydrogenase 1 (NADP+), soluble49400.7570.4963No
62FLJ42627NAFLJ42627
Entrez,  Source
-54530.6280.4807No
63C2orf27ANA56480.5880.4767No
64KIAA1310NA59500.5370.4684No
65GPD1LNAGPD1L
Entrez,  Source
glycerol-3-phosphate dehydrogenase 1-like59700.5330.4705No
66S100A4NAS100A4
Entrez,  Source
S100 calcium binding protein A460350.5210.4709No
67MSRB2NAMSRB2
Entrez,  Source
methionine sulfoxide reductase B262030.4970.4674No
68TNP1NATNP1
Entrez,  Source
transition protein 1 (during histone to protamine replacement)62880.4830.4668No
69WDR25NAWDR25
Entrez,  Source
WD repeat domain 2563870.4690.4657No
70DPYDNADPYD
Entrez,  Source
dihydropyrimidine dehydrogenase65990.4410.4602No
71TRAF3IP2NATRAF3IP2
Entrez,  Source
TRAF3 interacting protein 267490.4240.4569No
72HIST1H3GNAHIST1H3G
Entrez,  Source
histone cluster 1, H3g69770.4000.4507No
73MGC2889NAMGC2889
Entrez,  Source
-69780.4000.4528No
74ABHD8NAABHD8
Entrez,  Source
abhydrolase domain containing 872510.3710.4447No
75GPR88NAGPR88
Entrez,  Source
G protein-coupled receptor 8873820.3570.4418No
76PRDX2NAPRDX2
Entrez,  Source
peroxiredoxin 277790.3200.4289No
77ECH1NAECH1
Entrez,  Source
enoyl Coenzyme A hydratase 1, peroxisomal87140.2470.3959No
78TCEAL2NATCEAL2
Entrez,  Source
transcription elongation factor A (SII)-like 288030.2410.3939No
79ESRP1NA89000.2360.3916No
80MYH13NAMYH13
Entrez,  Source
myosin, heavy chain 13, skeletal muscle89530.2330.3909No
81MAOBNAMAOB
Entrez,  Source
monoamine oxidase B92850.2150.3799No
82PIK3R3NAPIK3R3
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)98410.1860.3604No
83TSPONATSPO
Entrez,  Source
translocator protein (18kDa)100240.1780.3547No
84BRCC3NABRCC3
Entrez,  Source
BRCA1/BRCA2-containing complex, subunit 3100950.1740.3530No
85SLPINASLPI
Entrez,  Source
secretory leukocyte peptidase inhibitor102260.1680.3491No
86FAM76ANAFAM76A
Entrez,  Source
family with sequence similarity 76, member A108930.1380.3253No
87KLF15NAKLF15
Entrez,  Source
Kruppel-like factor 15113480.1160.3092No
88ALX4NAALX4
Entrez,  Source
aristaless-like homeobox 4133620.0390.2354No
89SCNN1ANASCNN1A
Entrez,  Source
sodium channel, nonvoltage-gated 1 alpha134510.0350.2323No
90ARHGAP15NAARHGAP15
Entrez,  Source
Rho GTPase activating protein 15140930.0120.2088No
91GTF2A1LNA15724-0.0490.1491No
92LECT1NALECT1
Entrez,  Source
leukocyte cell derived chemotaxin 115777-0.0510.1475No
93SLC17A6NASLC17A6
Entrez,  Source
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 615850-0.0540.1451No
94TP63NA15864-0.0540.1449No
95PLAC4NAPLAC4
Entrez,  Source
placenta-specific 416126-0.0650.1357No
96LMO3NALMO3
Entrez,  Source
LIM domain only 3 (rhombotin-like 2)16466-0.0800.1236No
97CCKARNACCKAR
Entrez,  Source
cholecystokinin A receptor16682-0.0880.1162No
98STON1NASTON1
Entrez,  Source
stonin 116900-0.0970.1087No
99TFF2NATFF2
Entrez,  Source
trefoil factor 2 (spasmolytic protein 1)17043-0.1030.1040No
100PDCD4NAPDCD4
Entrez,  Source
programmed cell death 4 (neoplastic transformation inhibitor)17060-0.1040.1040No
101IFI27NAIFI27
Entrez,  Source
interferon, alpha-inducible protein 2717553-0.1270.0865No
102TEX14NATEX14
Entrez,  Source
testis expressed sequence 1418493-0.1850.0530No
103CDH22NACDH22
Entrez,  Source
cadherin-like 2218597-0.1930.0502No
104WNT16NAWNT16
Entrez,  Source
wingless-type MMTV integration site family, member 1619151-0.2390.0311No
105CTAG1ANACTAG1A
Entrez,  Source
cancer/testis antigen 1A19211-0.2450.0302No
106CES1NACES1
Entrez,  Source
carboxylesterase 1 (monocyte/macrophage serine esterase 1)19568-0.2770.0186No
107SIM1NASIM1
Entrez,  Source
single-minded homolog 1 (Drosophila)19952-0.3150.0062No
108SUCLG2NASUCLG2
Entrez,  Source
succinate-CoA ligase, GDP-forming, beta subunit20223-0.344-0.0020No
109CLDN16NACLDN16
Entrez,  Source
claudin 1620246-0.348-0.0010No
110TTC33NATTC33
Entrez,  Source
tetratricopeptide repeat domain 3320419-0.370-0.0053No
111SFXN1NASFXN1
Entrez,  Source
sideroflexin 120464-0.376-0.0050No
112EHHADHNAEHHADH
Entrez,  Source
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase20792-0.421-0.0148No
113RXRGNARXRG
Entrez,  Source
retinoid X receptor, gamma20994-0.451-0.0198No
114LANCL1NALANCL1
Entrez,  Source
LanC lantibiotic synthetase component C-like 1 (bacterial)21626-0.556-0.0401No
115PRPF6NAPRPF6
Entrez,  Source
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)21779-0.587-0.0426No
116SOD2NASOD2
Entrez,  Source
superoxide dismutase 2, mitochondrial21809-0.594-0.0406No
117LPAR2NA22257-0.679-0.0535No
118API5NAAPI5
Entrez,  Source
apoptosis inhibitor 522332-0.694-0.0526No
119PADI2NAPADI2
Entrez,  Source
peptidyl arginine deiminase, type II22773-0.789-0.0646No
120CYP11A1NACYP11A1
Entrez,  Source
cytochrome P450, family 11, subfamily A, polypeptide 122993-0.839-0.0683No
121CAB39NACAB39
Entrez,  Source
calcium binding protein 3922997-0.839-0.0640No
122TSPAN1NATSPAN1
Entrez,  Source
tetraspanin 123502-0.951-0.0775No
123CHMP2BNACHMP2B
Entrez,  Source
chromatin modifying protein 2B23563-0.969-0.0747No
124TFAP2ANATFAP2A
Entrez,  Source
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)23640-0.991-0.0723No
125BLVRBNABLVRB
Entrez,  Source
biliverdin reductase B (flavin reductase (NADPH))23893-1.062-0.0760No
126BMI1NABMI1
Entrez,  Source
B lymphoma Mo-MLV insertion region (mouse)23952-1.077-0.0725No
127MSX2NAMSX2
Entrez,  Source
msh homeobox homolog 2 (Drosophila)24841-1.357-0.0980No
128DDX60NA24864-1.366-0.0917No
129SNAI1NASNAI1
Entrez,  Source
snail homolog 1 (Drosophila)25400-1.593-0.1030No
130EIF4BNAEIF4B
Entrez,  Source
eukaryotic translation initiation factor 4B25595-1.686-0.1013No
131DNAJC12NADNAJC12
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily C, member 1225713-1.746-0.0964No
132IFI6NAIFI6
Entrez,  Source
interferon, alpha-inducible protein 625912-1.862-0.0940No
133MVPNAMVP
Entrez,  Source
major vault protein26105-1.983-0.0906No
134PDE5ANAPDE5A
Entrez,  Source
phosphodiesterase 5A, cGMP-specific26369-2.191-0.0888No
135EEF1A2NAEEF1A2
Entrez,  Source
eukaryotic translation elongation factor 1 alpha 226472-2.272-0.0806No
136ISOC1NAISOC1
Entrez,  Source
isochorismatase domain containing 126725-2.534-0.0766No
137SOCS2NASOCS2
Entrez,  Source
suppressor of cytokine signaling 226833-2.703-0.0664No
138PLS1NAPLS1
Entrez,  Source
plastin 1 (I isoform)26911-2.826-0.0544No
139C17orf59NAC17ORF59
Entrez,  Source
chromosome 17 open reading frame 5926922-2.858-0.0398No
140IL1R1NAIL1R1
Entrez,  Source
interleukin 1 receptor, type I26964-2.933-0.0259No
141TNNT1NATNNT1
Entrez,  Source
troponin T type 1 (skeletal, slow)27044-3.163-0.0123No
142EGR1NAEGR1
Entrez,  Source
early growth response 127274-4.3300.0020No
Table: GSEA details [plain text format]



Fig 2: BMI1_DN.V1_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: BMI1_DN.V1_DN: Random ES distribution   
Gene set null distribution of ES for BMI1_DN.V1_DN