Datasetexpression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls
#wt_versus_radiation.mainSample.cls
#wt_versus_radiation_repos
PhenotypemainSample.cls#wt_versus_radiation_repos
Upregulated in class2
GeneSetCORDENONSI_YAP_CONSERVED_SIGNATURE
Enrichment Score (ES)-0.3497458
Normalized Enrichment Score (NES)-1.2000318
Nominal p-value0.17842324
FDR q-value0.23659223
FWER p-Value0.918
Table: GSEA Results Summary



Fig 1: Enrichment plot: CORDENONSI_YAP_CONSERVED_SIGNATURE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PMP22NAPMP22
Entrez,  Source
peripheral myelin protein 22413.7130.0423No
2SCHIP1NASCHIP1
Entrez,  Source
schwannomin interacting protein 1663.5900.0838No
3CDKN2CNACDKN2C
Entrez,  Source
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)933.5070.1242No
4EMP2NAEMP2
Entrez,  Source
epithelial membrane protein 22203.2360.1578No
5LHFPNALHFP
Entrez,  Source
lipoma HMGIC fusion partner2653.1440.1933No
6FSCN1NAFSCN1
Entrez,  Source
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)9292.3660.1969No
7TNS1NATNS1
Entrez,  Source
tensin 19422.3600.2243No
8NDRG1NANDRG1
Entrez,  Source
N-myc downstream regulated gene 19882.3210.2501No
9ETV5NAETV5
Entrez,  Source
ets variant gene 5 (ets-related molecule)19911.7310.2337No
10PDLIM2NAPDLIM2
Entrez,  Source
PDZ and LIM domain 2 (mystique)21711.6450.2466No
11FSTL1NAFSTL1
Entrez,  Source
follistatin-like 122111.6290.2644No
12MARCKSNAMARCKS
Entrez,  Source
myristoylated alanine-rich protein kinase C substrate22931.5990.2803No
13TSPAN3NATSPAN3
Entrez,  Source
tetraspanin 329731.3180.2710No
14GLSNAGLS
Entrez,  Source
glutaminase29911.3130.2858No
15DDAH1NADDAH1
Entrez,  Source
dimethylarginine dimethylaminohydrolase 131321.2640.2956No
16SDPRNASDPR
Entrez,  Source
serum deprivation response (phosphatidylserine binding protein)35941.1200.2919No
17TGFB2NATGFB2
Entrez,  Source
transforming growth factor, beta 244140.8800.2723No
18AGFG2NA53030.6610.2475No
19STMN1NASTMN1
Entrez,  Source
stathmin 1/oncoprotein 1854640.6260.2491No
20ITGB5NAITGB5
Entrez,  Source
integrin, beta 555360.6100.2536No
21CENPFNACENPF
Entrez,  Source
centromere protein F, 350/400ka (mitosin)69840.3990.2053No
22GADD45BNAGADD45B
Entrez,  Source
growth arrest and DNA-damage-inducible, beta75520.3400.1885No
23TNNT2NATNNT2
Entrez,  Source
troponin T type 2 (cardiac)107480.1440.0731No
24CRIM1NACRIM1
Entrez,  Source
cysteine rich transmembrane BMP regulator 1 (chordin-like)123250.0780.0162No
25BICC1NABICC1
Entrez,  Source
bicaudal C homolog 1 (Drosophila)130450.051-0.0096No
26ANKRD1NAANKRD1
Entrez,  Source
ankyrin repeat domain 1 (cardiac muscle)132680.042-0.0172No
27FLNANAFLNA
Entrez,  Source
filamin A, alpha (actin binding protein 280)16587-0.084-0.1379No
28COL4A3NACOL4A3
Entrez,  Source
collagen, type IV, alpha 3 (Goodpasture antigen)16660-0.087-0.1395No
29ASAP1NA17762-0.138-0.1782No
30CYR61NACYR61
Entrez,  Source
cysteine-rich, angiogenic inducer, 6119423-0.263-0.2360No
31FGF2NAFGF2
Entrez,  Source
fibroblast growth factor 2 (basic)20293-0.354-0.2637No
32DUTNADUT
Entrez,  Source
dUTP pyrophosphatase21369-0.509-0.2971No
33HEXBNAHEXB
Entrez,  Source
hexosaminidase B (beta polypeptide)21446-0.525-0.2937No
34TOP2ANATOP2A
Entrez,  Source
topoisomerase (DNA) II alpha 170kDa21883-0.606-0.3025No
35PHGDHNAPHGDH
Entrez,  Source
phosphoglycerate dehydrogenase22483-0.726-0.3159No
36BIRC5NABIRC5
Entrez,  Source
baculoviral IAP repeat-containing 5 (survivin)22533-0.737-0.3090No
37GGHNAGGH
Entrez,  Source
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)23100-0.858-0.3196No
38ECT2NAECT2
Entrez,  Source
epithelial cell transforming sequence 2 oncogene23923-1.071-0.3371Yes
39SERPINE1NASERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 124193-1.147-0.3334Yes
40THBS1NATHBS1
Entrez,  Source
thrombospondin 124222-1.157-0.3208Yes
41TK1NATK1
Entrez,  Source
thymidine kinase 1, soluble24625-1.283-0.3204Yes
42HMMRNAHMMR
Entrez,  Source
hyaluronan-mediated motility receptor (RHAMM)24674-1.301-0.3068Yes
43ITGB2NAITGB2
Entrez,  Source
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)24721-1.317-0.2930Yes
44DUSP1NADUSP1
Entrez,  Source
dual specificity phosphatase 124798-1.344-0.2799Yes
45SGK1NA25489-1.638-0.2859Yes
46DLC1NADLC1
Entrez,  Source
deleted in liver cancer 125743-1.761-0.2743Yes
47GAS6NAGAS6
Entrez,  Source
growth arrest-specific 625863-1.837-0.2570Yes
48CTGFNACTGF
Entrez,  Source
connective tissue growth factor26085-1.972-0.2419Yes
49AMOTL2NAAMOTL2
Entrez,  Source
angiomotin like 226277-2.110-0.2240Yes
50SHCBP1NASHCBP1
Entrez,  Source
SHC SH2-domain binding protein 126401-2.215-0.2023Yes
51CDC20NACDC20
Entrez,  Source
CDC20 cell division cycle 20 homolog (S. cerevisiae)26422-2.230-0.1767Yes
52SLIT2NASLIT2
Entrez,  Source
slit homolog 2 (Drosophila)26489-2.288-0.1522Yes
53SH2D4ANASH2D4A
Entrez,  Source
SH2 domain containing 4A26528-2.322-0.1261Yes
54TGM2NATGM2
Entrez,  Source
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)26716-2.524-0.1032Yes
55DAB2NADAB2
Entrez,  Source
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)27101-3.363-0.0776Yes
56MDFICNAMDFIC
Entrez,  Source
MyoD family inhibitor domain containing27169-3.607-0.0375Yes
57AXLNAAXL
Entrez,  Source
AXL receptor tyrosine kinase27177-3.6710.0056Yes
Table: GSEA details [plain text format]



Fig 2: CORDENONSI_YAP_CONSERVED_SIGNATURE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: CORDENONSI_YAP_CONSERVED_SIGNATURE: Random ES distribution   
Gene set null distribution of ES for CORDENONSI_YAP_CONSERVED_SIGNATURE