Datasetexpression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls
#wt_versus_radiation.mainSample.cls
#wt_versus_radiation_repos
PhenotypemainSample.cls#wt_versus_radiation_repos
Upregulated in class2
GeneSetNRL_DN.V1_UP
Enrichment Score (ES)-0.30940127
Normalized Enrichment Score (NES)-1.2117006
Nominal p-value0.15353535
FDR q-value0.24705233
FWER p-Value0.907
Table: GSEA Results Summary



Fig 1: Enrichment plot: NRL_DN.V1_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1IGFBP5NAIGFBP5
Entrez,  Source
insulin-like growth factor binding protein 5103.9870.0274No
2APC2NAAPC2
Entrez,  Source
adenomatosis polyposis coli 21453.3660.0458No
3LMO1NALMO1
Entrez,  Source
LIM domain only 1 (rhombotin 1)4142.9070.0562No
4ST8SIA1NAST8SIA1
Entrez,  Source
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 15772.6930.0690No
5MEF2CNAMEF2C
Entrez,  Source
MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C)6482.6220.0846No
6GADD45ANAGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha7932.4790.0965No
7RFX2NARFX2
Entrez,  Source
regulatory factor X, 2 (influences HLA class II expression)10612.2710.1025No
8TAOK3NATAOK3
Entrez,  Source
TAO kinase 311182.2350.1160No
9ST3GAL1NAST3GAL1
Entrez,  Source
ST3 beta-galactoside alpha-2,3-sialyltransferase 113682.0600.1212No
10BCL2L11NABCL2L11
Entrez,  Source
BCL2-like 11 (apoptosis facilitator)13772.0560.1352No
11GNB1NAGNB1
Entrez,  Source
guanine nucleotide binding protein (G protein), beta polypeptide 113852.0510.1492No
12DPF3NADPF3
Entrez,  Source
D4, zinc and double PHD fingers, family 314532.0050.1606No
13BCL3NABCL3
Entrez,  Source
B-cell CLL/lymphoma 315231.9650.1718No
14WISP1NAWISP1
Entrez,  Source
WNT1 inducible signaling pathway protein 115681.9410.1836No
15SAP30NASAP30
Entrez,  Source
Sin3A-associated protein, 30kDa17261.8590.1908No
16AQP1NAAQP1
Entrez,  Source
aquaporin 1 (Colton blood group)18111.8160.2003No
17AHRRNAAHRR
Entrez,  Source
aryl-hydrocarbon receptor repressor18401.8060.2119No
18BBS9NA18871.7840.2226No
19NLGN2NANLGN2
Entrez,  Source
neuroligin 219091.7730.2341No
20RHBDL3NARHBDL3
Entrez,  Source
rhomboid, veinlet-like 3 (Drosophila)19421.7560.2452No
21ELAVL3NAELAVL3
Entrez,  Source
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)19761.7380.2560No
22DIRAS1NADIRAS1
Entrez,  Source
DIRAS family, GTP-binding RAS-like 120041.7220.2670No
23PLEKHA2NAPLEKHA2
Entrez,  Source
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 222331.6220.2699No
24CALUNACALU
Entrez,  Source
calumenin23071.5920.2783No
25MLL3NAMLL3
Entrez,  Source
myeloid/lymphoid or mixed-lineage leukemia 333111.2100.2498No
26GAS7NAGAS7
Entrez,  Source
growth arrest-specific 735201.1480.2502No
27PDE6BNAPDE6B
Entrez,  Source
phosphodiesterase 6B, cGMP-specific, rod, beta (congenital stationary night blindness 3, autosomal dominant)36241.1080.2541No
28GPSM2NAGPSM2
Entrez,  Source
G-protein signalling modulator 2 (AGS3-like, C. elegans)42090.9290.2390No
29SCN2ANA50720.7280.2124No
30ZFP36L2NAZFP36L2
Entrez,  Source
zinc finger protein 36, C3H type-like 251440.7090.2147No
31GALNT7NAGALNT7
Entrez,  Source
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)52360.6820.2161No
32CNOT3NACNOT3
Entrez,  Source
CCR4-NOT transcription complex, subunit 352840.6660.2190No
33EDN2NAEDN2
Entrez,  Source
endothelin 253420.6510.2215No
34ALPLNAALPL
Entrez,  Source
alkaline phosphatase, liver/bone/kidney54000.6380.2238No
35NME4NANME4
Entrez,  Source
non-metastatic cells 4, protein expressed in56130.5950.2201No
36PLEKHF2NAPLEKHF2
Entrez,  Source
pleckstrin homology domain containing, family F (with FYVE domain) member 256460.5880.2231No
37NRLNANRL
Entrez,  Source
neural retina leucine zipper58100.5590.2209No
38SEC14L2NASEC14L2
Entrez,  Source
SEC14-like 2 (S. cerevisiae)58820.5500.2222No
39ZDHHC6NAZDHHC6
Entrez,  Source
zinc finger, DHHC-type containing 659610.5350.2230No
40CDK5R2NACDK5R2
Entrez,  Source
cyclin-dependent kinase 5, regulatory subunit 2 (p39)63230.4780.2131No
41PRM3NAPRM3
Entrez,  Source
protamine 363650.4710.2148No
42POLR2ANAPOLR2A
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa65070.4520.2128No
43PPAP2CNAPPAP2C
Entrez,  Source
phosphatidic acid phosphatase type 2C66410.4360.2109No
44PTPRCAPNAPTPRCAP
Entrez,  Source
protein tyrosine phosphatase, receptor type, C-associated protein67620.4220.2095No
45PLAGL2NAPLAGL2
Entrez,  Source
pleiomorphic adenoma gene-like 272420.3720.1944No
46CRYGANACRYGA
Entrez,  Source
crystallin, gamma A73270.3620.1939No
47MLLNAMLL
Entrez,  Source
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)74250.3510.1927No
48SPENNASPEN
Entrez,  Source
spen homolog, transcriptional regulator (Drosophila)76830.3270.1855No
49CALN1NACALN1
Entrez,  Source
calneuron 186020.2560.1536No
50TAS2R4NATAS2R4
Entrez,  Source
taste receptor, type 2, member 488620.2380.1457No
51TCP11NATCP11
Entrez,  Source
t-complex 11 (mouse)92330.2170.1336No
52GNAT1NAGNAT1
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 192430.2170.1348No
53PCOLCENAPCOLCE
Entrez,  Source
procollagen C-endopeptidase enhancer101930.1700.1011No
54SEMA4GNASEMA4G
Entrez,  Source
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G103860.1610.0951No
55PPP1R3ANAPPP1R3A
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 3A (glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle)106570.1490.0862No
56TNNT2NATNNT2
Entrez,  Source
troponin T type 2 (cardiac)107480.1440.0839No
57ESRRBNAESRRB
Entrez,  Source
estrogen-related receptor beta108710.1380.0804No
58SLC24A1NASLC24A1
Entrez,  Source
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1112150.1220.0686No
59ZC3H3NAZC3H3
Entrez,  Source
zinc finger CCCH-type containing 3112550.1200.0680No
60RHONARHO
Entrez,  Source
rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant)117180.1010.0518No
61GALNT10NAGALNT10
Entrez,  Source
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)117320.1000.0520No
62SOX15NASOX15
Entrez,  Source
SRY (sex determining region Y)-box 15117850.0980.0508No
63STK17BNASTK17B
Entrez,  Source
serine/threonine kinase 17b (apoptosis-inducing)119360.0930.0459No
64SLC26A8NASLC26A8
Entrez,  Source
solute carrier family 26, member 8119610.0920.0456No
65C10orf99NAC10ORF99
Entrez,  Source
chromosome 10 open reading frame 99122030.0820.0373No
66RHPN1NARHPN1
Entrez,  Source
rhophilin, Rho GTPase binding protein 1124720.0720.0280No
67CSDC2NACSDC2
Entrez,  Source
cold shock domain containing C2, RNA binding128140.0600.0159No
68ACVR2BNAACVR2B
Entrez,  Source
activin A receptor, type IIB131390.0470.0043No
69LAD1NALAD1
Entrez,  Source
ladinin 1131680.0460.0036No
70IL1F10NAIL1F10
Entrez,  Source
interleukin 1 family, member 10 (theta)133600.039-0.0032No
71SUPT6HNASUPT6H
Entrez,  Source
suppressor of Ty 6 homolog (S. cerevisiae)135650.030-0.0105No
72HAS1NAHAS1
Entrez,  Source
hyaluronan synthase 1140980.012-0.0299No
73KCNB1NAKCNB1
Entrez,  Source
potassium voltage-gated channel, Shab-related subfamily, member 1143400.003-0.0388No
74NR2E3NANR2E3
Entrez,  Source
nuclear receptor subfamily 2, group E, member 314893-0.017-0.0590No
75TFF3NATFF3
Entrez,  Source
trefoil factor 3 (intestinal)15504-0.041-0.0811No
76ATP8A2NAATP8A2
Entrez,  Source
ATPase, aminophospholipid transporter-like, Class I, type 8A, member 215641-0.046-0.0858No
77GRIP1NAGRIP1
Entrez,  Source
glutamate receptor interacting protein 115922-0.056-0.0957No
78PLA2R1NAPLA2R1
Entrez,  Source
phospholipase A2 receptor 1, 180kDa16358-0.076-0.1112No
79SH2D1ANASH2D1A
Entrez,  Source
SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome)16694-0.089-0.1229No
80CCDC64NACCDC64
Entrez,  Source
coiled-coil domain containing 6417110-0.106-0.1374No
81IMPG1NAIMPG1
Entrez,  Source
interphotoreceptor matrix proteoglycan 117119-0.107-0.1369No
82NXNL1NA17327-0.116-0.1438No
83FOXH1NAFOXH1
Entrez,  Source
forkhead box H117430-0.121-0.1467No
84SAMD11NASAMD11
Entrez,  Source
sterile alpha motif domain containing 1117888-0.147-0.1624No
85STK35NASTK35
Entrez,  Source
serine/threonine kinase 3518257-0.169-0.1748No
86NGDNNANGDN
Entrez,  Source
neuroguidin, EIF4E binding protein18268-0.170-0.1740No
87CDR2NACDR2
Entrez,  Source
cerebellar degeneration-related protein 2, 62kDa18628-0.196-0.1858No
88GRIK5NAGRIK5
Entrez,  Source
glutamate receptor, ionotropic, kainate 518885-0.216-0.1937No
89TRPC1NATRPC1
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 119500-0.270-0.2144No
90CNGA1NACNGA1
Entrez,  Source
cyclic nucleotide gated channel alpha 120048-0.326-0.2323No
91B4GALT1NAB4GALT1
Entrez,  Source
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 120527-0.383-0.2472No
92COL19A1NACOL19A1
Entrez,  Source
collagen, type XIX, alpha 120601-0.393-0.2472No
93EBPLNAEBPL
Entrez,  Source
emopamil binding protein-like20617-0.395-0.2450No
94MC1RNAMC1R
Entrez,  Source
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)21346-0.506-0.2682No
95DUSP14NADUSP14
Entrez,  Source
dual specificity phosphatase 1421366-0.509-0.2654No
96HIC2NAHIC2
Entrez,  Source
hypermethylated in cancer 221620-0.555-0.2708No
97ARG2NAARG2
Entrez,  Source
arginase, type II21927-0.613-0.2778No
98DHRS3NADHRS3
Entrez,  Source
dehydrogenase/reductase (SDR family) member 322386-0.704-0.2898No
99IRF6NAIRF6
Entrez,  Source
interferon regulatory factor 622539-0.740-0.2902No
100GRTP1NAGRTP1
Entrez,  Source
growth hormone regulated TBC protein 122683-0.770-0.2901No
101KCNN4NAKCNN4
Entrez,  Source
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 423007-0.840-0.2961No
102KCNJ14NAKCNJ14
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 1423202-0.880-0.2972No
103TNFAIP3NATNFAIP3
Entrez,  Source
tumor necrosis factor, alpha-induced protein 323231-0.887-0.2920No
104PPARANAPPARA
Entrez,  Source
peroxisome proliferative activated receptor, alpha23325-0.907-0.2891No
105MLF1NAMLF1
Entrez,  Source
myeloid leukemia factor 123877-1.059-0.3020Yes
106PDE6ANAPDE6A
Entrez,  Source
phosphodiesterase 6A, cGMP-specific, rod, alpha24050-1.104-0.3007Yes
107STYXNASTYX
Entrez,  Source
serine/threonine/tyrosine interacting protein24104-1.120-0.2948Yes
108BST1NABST1
Entrez,  Source
bone marrow stromal cell antigen 124154-1.136-0.2888Yes
109LRRC2NALRRC2
Entrez,  Source
leucine rich repeat containing 224238-1.161-0.2837Yes
110SNTB2NASNTB2
Entrez,  Source
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)24643-1.291-0.2896Yes
111SLC16A6NASLC16A6
Entrez,  Source
solute carrier family 16, member 6 (monocarboxylic acid transporter 7)24660-1.296-0.2812Yes
112TTC39CNA24663-1.297-0.2722Yes
113SNTA1NASNTA1
Entrez,  Source
syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)24914-1.385-0.2718Yes
114C10orf47NAC10ORF47
Entrez,  Source
chromosome 10 open reading frame 4725034-1.432-0.2662Yes
115PDIA5NAPDIA5
Entrez,  Source
protein disulfide isomerase family A, member 525079-1.452-0.2578Yes
116FAIMNAFAIM
Entrez,  Source
Fas apoptotic inhibitory molecule25124-1.473-0.2491Yes
117NUF2NA25290-1.544-0.2445Yes
118ARHGAP10NAARHGAP10
Entrez,  Source
Rho GTPase activating protein 1025435-1.610-0.2386Yes
119KLHL36NA25442-1.612-0.2276Yes
120POLG2NAPOLG2
Entrez,  Source
polymerase (DNA directed), gamma 2, accessory subunit25575-1.677-0.2208Yes
121ARMC1NAARMC1
Entrez,  Source
armadillo repeat containing 125670-1.721-0.2123Yes
122SNTG2NASNTG2
Entrez,  Source
syntrophin, gamma 225788-1.785-0.2042Yes
123REEP6NAREEP6
Entrez,  Source
receptor accessory protein 625886-1.850-0.1949Yes
124RNF207NARNF207
Entrez,  Source
ring finger protein 20726043-1.945-0.1871Yes
125CCNA2NACCNA2
Entrez,  Source
cyclin A226210-2.066-0.1788Yes
126EML3NAEML3
Entrez,  Source
echinoderm microtubule associated protein like 326296-2.126-0.1672Yes
127PPARGC1BNAPPARGC1B
Entrez,  Source
peroxisome proliferative activated receptor, gamma, coactivator 1, beta26621-2.408-0.1623Yes
128SHISA2NA26634-2.422-0.1459Yes
129STARD10NASTARD10
Entrez,  Source
START domain containing 1026945-2.900-0.1372Yes
130SLC29A2NASLC29A2
Entrez,  Source
solute carrier family 29 (nucleoside transporters), member 226988-3.010-0.1178Yes
131EXT1NAEXT1
Entrez,  Source
exostoses (multiple) 127055-3.195-0.0980Yes
132MKNK1NAMKNK1
Entrez,  Source
MAP kinase interacting serine/threonine kinase 127056-3.195-0.0758Yes
133CLDN23NACLDN23
Entrez,  Source
claudin 2327232-4.022-0.0542Yes
134LLGL2NALLGL2
Entrez,  Source
lethal giant larvae homolog 2 (Drosophila)27234-4.038-0.0262Yes
135TNFAIP2NATNFAIP2
Entrez,  Source
tumor necrosis factor, alpha-induced protein 227266-4.2660.0023Yes
Table: GSEA details [plain text format]



Fig 2: NRL_DN.V1_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: NRL_DN.V1_UP: Random ES distribution   
Gene set null distribution of ES for NRL_DN.V1_UP