Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | ACTIVATION_OF_IMMUNE_RESPONSE |
| Enrichment Score (ES) | 0.7585143 |
| Normalized Enrichment Score (NES) | 2.0850358 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.001053719 |
| FWER p-Value | 0.001 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | THY1 | NA | THY1 Entrez, Source | Thy-1 cell surface antigen | 240 | 3.194 | 0.2388 | Yes |
| 2 | FYN | NA | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 290 | 3.102 | 0.4774 | Yes |
| 3 | UBE2N | NA | UBE2N Entrez, Source | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | 1299 | 2.102 | 0.6034 | Yes |
| 4 | TRAF6 | NA | TRAF6 Entrez, Source | TNF receptor-associated factor 6 | 1389 | 2.044 | 0.7585 | Yes |
| 5 | CD79A | NA | CD79A Entrez, Source | CD79a molecule, immunoglobulin-associated alpha | 7709 | 0.325 | 0.5523 | No |
| 6 | MALT1 | NA | MALT1 Entrez, Source | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 9281 | 0.215 | 0.5114 | No |
| 7 | MBL2 | NA | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 9779 | 0.189 | 0.5079 | No |
| 8 | SLA2 | NA | SLA2 Entrez, Source | Src-like-adaptor 2 | 10157 | 0.172 | 0.5074 | No |
| 9 | TRAT1 | NA | TRAT1 Entrez, Source | T cell receptor associated transmembrane adaptor 1 | 12290 | 0.080 | 0.4355 | No |
| 10 | LAT2 | NA | LAT2 Entrez, Source | linker for activation of T cells family, member 2 | 13288 | 0.042 | 0.4022 | No |
| 11 | C2 | NA | C2 Entrez, Source | complement component 2 | 13410 | 0.037 | 0.4007 | No |
| 12 | KRT1 | NA | KRT1 Entrez, Source | keratin 1 (epidermolytic hyperkeratosis) | 14206 | 0.008 | 0.3722 | No |
| 13 | PTPRC | NA | PTPRC Entrez, Source | protein tyrosine phosphatase, receptor type, C | 15992 | -0.059 | 0.3114 | No |
| 14 | CFHR1 | NA | CFHR1 Entrez, Source | complement factor H-related 1 | 16434 | -0.079 | 0.3014 | No |
| 15 | NFAM1 | NA | NFAM1 Entrez, Source | NFAT activating protein with ITAM motif 1 | 16832 | -0.094 | 0.2941 | No |
| 16 | IKBKG | NA | IKBKG Entrez, Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 17316 | -0.116 | 0.2854 | No |
| 17 | BCAR1 | NA | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 23839 | -1.047 | 0.1278 | No |
