Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | AEROBIC_RESPIRATION |
| Enrichment Score (ES) | -0.62342805 |
| Normalized Enrichment Score (NES) | -1.545948 |
| Nominal p-value | 0.012269938 |
| FDR q-value | 0.16338296 |
| FWER p-Value | 0.678 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SURF1 | NA | SURF1 Entrez, Source | surfeit 1 | 2084 | 1.684 | 0.0155 | No |
| 2 | NNT | NA | NNT Entrez, Source | nicotinamide nucleotide transhydrogenase | 2592 | 1.464 | 0.0768 | No |
| 3 | ACO2 | NA | ACO2 Entrez, Source | aconitase 2, mitochondrial | 5466 | 0.625 | 0.0057 | No |
| 4 | UQCRC1 | NA | UQCRC1 Entrez, Source | ubiquinol-cytochrome c reductase core protein I | 8350 | 0.273 | -0.0849 | No |
| 5 | SDHD | NA | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 14228 | 0.007 | -0.2997 | No |
| 6 | UQCRH | NA | UQCRH Entrez, Source | ubiquinol-cytochrome c reductase hinge protein | 15717 | -0.049 | -0.3515 | No |
| 7 | SDHC | NA | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 17254 | -0.113 | -0.4016 | No |
| 8 | SLC25A14 | NA | SLC25A14 Entrez, Source | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 17765 | -0.138 | -0.4128 | No |
| 9 | UQCRC2 | NA | UQCRC2 Entrez, Source | ubiquinol-cytochrome c reductase core protein II | 23520 | -0.957 | -0.5713 | Yes |
| 10 | SDHA | NA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 24098 | -1.117 | -0.5315 | Yes |
| 11 | UQCRB | NA | UQCRB Entrez, Source | ubiquinol-cytochrome c reductase binding protein | 24830 | -1.354 | -0.4844 | Yes |
| 12 | PDHB | NA | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 25712 | -1.746 | -0.4215 | Yes |
| 13 | SDHB | NA | SDHB Entrez, Source | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 26218 | -2.072 | -0.3270 | Yes |
| 14 | OXA1L | NA | OXA1L Entrez, Source | oxidase (cytochrome c) assembly 1-like | 26339 | -2.161 | -0.2136 | Yes |
| 15 | ME3 | NA | ME3 Entrez, Source | malic enzyme 3, NADP(+)-dependent, mitochondrial | 27298 | -4.582 | 0.0011 | Yes |
