Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | COFACTOR_BIOSYNTHETIC_PROCESS |
| Enrichment Score (ES) | -0.5482717 |
| Normalized Enrichment Score (NES) | -1.5776023 |
| Nominal p-value | 0.01268499 |
| FDR q-value | 0.17452493 |
| FWER p-Value | 0.599 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | NFE2L1 | NA | NFE2L1 Entrez, Source | nuclear factor (erythroid-derived 2)-like 1 | 1666 | 1.889 | 0.0095 | No |
| 2 | FECH | NA | FECH Entrez, Source | ferrochelatase (protoporphyria) | 2381 | 1.557 | 0.0415 | No |
| 3 | MOCS2 | NA | MOCS2 Entrez, Source | molybdenum cofactor synthesis 2 | 2627 | 1.450 | 0.0866 | No |
| 4 | COQ7 | NA | COQ7 Entrez, Source | coenzyme Q7 homolog, ubiquinone (yeast) | 3434 | 1.173 | 0.1009 | No |
| 5 | UROS | NA | UROS Entrez, Source | uroporphyrinogen III synthase (congenital erythropoietic porphyria) | 4567 | 0.847 | 0.0910 | No |
| 6 | ALAD | NA | ALAD Entrez, Source | aminolevulinate, delta-, dehydratase | 5304 | 0.661 | 0.0887 | No |
| 7 | TSPO | NA | TSPO Entrez, Source | translocator protein (18kDa) | 10024 | 0.178 | -0.0774 | No |
| 8 | GCLM | NA | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 14683 | -0.009 | -0.2477 | No |
| 9 | ALAS2 | NA | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 18816 | -0.211 | -0.3911 | No |
| 10 | PPOX | NA | PPOX Entrez, Source | protoporphyrinogen oxidase | 19682 | -0.287 | -0.4120 | No |
| 11 | COX15 | NA | COX15 Entrez, Source | COX15 homolog, cytochrome c oxidase assembly protein (yeast) | 19946 | -0.315 | -0.4099 | No |
| 12 | COASY | NA | COASY Entrez, Source | Coenzyme A synthase | 23004 | -0.840 | -0.4905 | No |
| 13 | PDSS1 | NA | PDSS1 Entrez, Source | prenyl (decaprenyl) diphosphate synthase, subunit 1 | 24583 | -1.273 | -0.5008 | Yes |
| 14 | ALAS1 | NA | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 24845 | -1.358 | -0.4596 | Yes |
| 15 | COQ2 | NA | COQ2 Entrez, Source | coenzyme Q2 homolog, prenyltransferase (yeast) | 25657 | -1.715 | -0.4253 | Yes |
| 16 | CPOX | NA | CPOX Entrez, Source | coproporphyrinogen oxidase | 25836 | -1.815 | -0.3641 | Yes |
| 17 | COX10 | NA | COX10 Entrez, Source | COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) | 25950 | -1.884 | -0.2979 | Yes |
| 18 | GCLC | NA | GCLC Entrez, Source | glutamate-cysteine ligase, catalytic subunit | 26243 | -2.083 | -0.2309 | Yes |
| 19 | PDSS2 | NA | PDSS2 Entrez, Source | prenyl (decaprenyl) diphosphate synthase, subunit 2 | 26245 | -2.085 | -0.1531 | Yes |
| 20 | ME1 | NA | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 26454 | -2.261 | -0.0764 | Yes |
| 21 | COQ3 | NA | COQ3 Entrez, Source | coenzyme Q3 homolog, methyltransferase (S. cerevisiae) | 26947 | -2.903 | 0.0140 | Yes |
