Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | GLYCOLIPID_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.7336277 |
| Normalized Enrichment Score (NES) | 1.7814739 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.02911677 |
| FWER p-Value | 0.143 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ST8SIA1 | NA | ST8SIA1 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 | 577 | 2.693 | 0.1249 | Yes |
| 2 | ST6GALNAC6 | NA | ST6GALNAC6 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 | 865 | 2.419 | 0.2456 | Yes |
| 3 | PSAP | NA | PSAP Entrez, Source | prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) | 903 | 2.388 | 0.3737 | Yes |
| 4 | ST3GAL6 | NA | ST3GAL6 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 923 | 2.370 | 0.5015 | Yes |
| 5 | ST8SIA5 | NA | ST8SIA5 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 | 1033 | 2.296 | 0.6221 | Yes |
| 6 | B3GNT5 | NA | B3GNT5 Entrez, Source | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 1205 | 2.173 | 0.7336 | Yes |
| 7 | B4GALNT1 | NA | B4GALNT1 Entrez, Source | beta-1,4-N-acetyl-galactosaminyl transferase 1 | 4609 | 0.840 | 0.6546 | No |
| 8 | LARGE | NA | LARGE Entrez, Source | like-glycosyltransferase | 5365 | 0.646 | 0.6620 | No |
| 9 | CLN3 | NA | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 10400 | 0.160 | 0.4864 | No |
| 10 | ST8SIA3 | NA | ST8SIA3 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 | 13913 | 0.018 | 0.3588 | No |
| 11 | GBGT1 | NA | GBGT1 Entrez, Source | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 | 16541 | -0.083 | 0.2671 | No |
| 12 | ST6GALNAC4 | NA | ST6GALNAC4 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 | 16612 | -0.085 | 0.2691 | No |
| 13 | CLN6 | NA | CLN6 Entrez, Source | ceroid-lipofuscinosis, neuronal 6, late infantile, variant | 16971 | -0.100 | 0.2614 | No |
| 14 | GLA | NA | GLA Entrez, Source | galactosidase, alpha | 18643 | -0.197 | 0.2109 | No |
| 15 | NEU3 | NA | NEU3 Entrez, Source | sialidase 3 (membrane sialidase) | 22517 | -0.733 | 0.1089 | No |
| 16 | UGCG | NA | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 24492 | -1.240 | 0.1039 | No |
