Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
Phenotype | mainSample.cls#wt_versus_radiation_repos |
Upregulated in class | 2 |
GeneSet | HEMOPOIETIC_OR_LYMPHOID_ORGAN_DEVELOPMENT |
Enrichment Score (ES) | -0.4023755 |
Normalized Enrichment Score (NES) | -1.5560699 |
Nominal p-value | 0.01268499 |
FDR q-value | 0.16536614 |
FWER p-Value | 0.656 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | HDAC5 | NA | HDAC5 Entrez,  Source | histone deacetylase 5 | 620 | 2.653 | 0.0199 | No |
2 | CDK6 | NA | CDK6 Entrez,  Source | cyclin-dependent kinase 6 | 774 | 2.496 | 0.0543 | No |
3 | RAG1 | NA | RAG1 Entrez,  Source | recombination activating gene 1 | 842 | 2.440 | 0.0911 | No |
4 | NOTCH4 | NA | NOTCH4 Entrez,  Source | Notch homolog 4 (Drosophila) | 877 | 2.408 | 0.1285 | No |
5 | ZBTB16 | NA | ZBTB16 Entrez,  Source | zinc finger and BTB domain containing 16 | 1236 | 2.142 | 0.1498 | No |
6 | NOTCH2 | NA | NOTCH2 Entrez,  Source | Notch homolog 2 (Drosophila) | 2909 | 1.346 | 0.1100 | No |
7 | NCOA6 | NA | NCOA6 Entrez,  Source | nuclear receptor coactivator 6 | 3451 | 1.168 | 0.1090 | No |
8 | RUNX1 | NA | RUNX1 Entrez,  Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 3716 | 1.078 | 0.1166 | No |
9 | ZNF675 | NA | ZNF675 Entrez,  Source | zinc finger protein 675 | 4070 | 0.967 | 0.1192 | No |
10 | TGFB2 | NA | TGFB2 Entrez,  Source | transforming growth factor, beta 2 | 4414 | 0.880 | 0.1207 | No |
11 | KIRREL3 | NA | KIRREL3 Entrez,  Source | kin of IRRE like 3 (Drosophila) | 4586 | 0.843 | 0.1280 | No |
12 | MAFB | NA | MAFB Entrez,  Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) | 5115 | 0.716 | 0.1201 | No |
13 | CD3D | NA | CD3D Entrez,  Source | CD3d molecule, delta (CD3-TCR complex) | 5535 | 0.610 | 0.1145 | No |
14 | LDB1 | NA | LDB1 Entrez,  Source | LIM domain binding 1 | 6304 | 0.481 | 0.0941 | No |
15 | CDC42 | NA | CDC42 Entrez,  Source | cell division cycle 42 (GTP binding protein, 25kDa) | 6315 | 0.479 | 0.1014 | No |
16 | ACVR2A | NA | ACVR2A Entrez,  Source | activin A receptor, type IIA | 6330 | 0.476 | 0.1085 | No |
17 | CSF1 | NA | CSF1 Entrez,  Source | colony stimulating factor 1 (macrophage) | 6852 | 0.412 | 0.0960 | No |
18 | MLL | NA | MLL Entrez,  Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) | 7425 | 0.351 | 0.0807 | No |
19 | CD79A | NA | CD79A Entrez,  Source | CD79a molecule, immunoglobulin-associated alpha | 7709 | 0.325 | 0.0755 | No |
20 | LRMP | NA | LRMP Entrez,  Source | lymphoid-restricted membrane protein | 8098 | 0.292 | 0.0660 | No |
21 | HDAC9 | NA | HDAC9 Entrez,  Source | histone deacetylase 9 | 8162 | 0.287 | 0.0683 | No |
22 | IL2 | NA | IL2 Entrez,  Source | interleukin 2 | 8575 | 0.258 | 0.0573 | No |
23 | FOXO3 | NA | 8956 | 0.232 | 0.0471 | No | ||
24 | MAL | NA | MAL Entrez,  Source | mal, T-cell differentiation protein | 8971 | 0.232 | 0.0503 | No |
25 | SCIN | NA | SCIN Entrez,  Source | scinderin | 9244 | 0.216 | 0.0438 | No |
26 | INHA | NA | INHA Entrez,  Source | inhibin, alpha | 9461 | 0.205 | 0.0392 | No |
27 | SNRK | NA | SNRK Entrez,  Source | SNF related kinase | 9984 | 0.179 | 0.0229 | No |
28 | HDAC4 | NA | HDAC4 Entrez,  Source | histone deacetylase 4 | 10190 | 0.170 | 0.0181 | No |
29 | CD4 | NA | CD4 Entrez,  Source | CD4 molecule | 10391 | 0.161 | 0.0134 | No |
30 | TM7SF4 | NA | TM7SF4 Entrez,  Source | transmembrane 7 superfamily member 4 | 10640 | 0.150 | 0.0067 | No |
31 | BLNK | NA | BLNK Entrez,  Source | B-cell linker | 11083 | 0.128 | -0.0075 | No |
32 | INHBA | NA | INHBA Entrez,  Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 11814 | 0.097 | -0.0327 | No |
33 | IL4 | NA | IL4 Entrez,  Source | interleukin 4 | 12003 | 0.090 | -0.0382 | No |
34 | IL12B | NA | IL12B Entrez,  Source | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 12329 | 0.078 | -0.0488 | No |
35 | SPINK5 | NA | SPINK5 Entrez,  Source | serine peptidase inhibitor, Kazal type 5 | 12331 | 0.078 | -0.0476 | No |
36 | TAZ | NA | TAZ Entrez,  Source | tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) | 12468 | 0.072 | -0.0515 | No |
37 | RASGRP4 | NA | RASGRP4 Entrez,  Source | RAS guanyl releasing protein 4 | 13385 | 0.038 | -0.0845 | No |
38 | SPI1 | NA | SPI1 Entrez,  Source | spleen focus forming virus (SFFV) proviral integration oncogene spi1 | 13822 | 0.021 | -0.1001 | No |
39 | CARTPT | NA | CARTPT Entrez,  Source | CART prepropeptide | 14067 | 0.012 | -0.1089 | No |
40 | CALCA | NA | CALCA Entrez,  Source | calcitonin/calcitonin-related polypeptide, alpha | 15001 | -0.021 | -0.1427 | No |
41 | CD1D | NA | CD1D Entrez,  Source | CD1d molecule | 15044 | -0.023 | -0.1439 | No |
42 | PF4 | NA | PF4 Entrez,  Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 15523 | -0.042 | -0.1608 | No |
43 | SART1 | NA | SART1 Entrez,  Source | squamous cell carcinoma antigen recognised by T cells | 15650 | -0.046 | -0.1647 | No |
44 | PTPRC | NA | PTPRC Entrez,  Source | protein tyrosine phosphatase, receptor type, C | 15992 | -0.059 | -0.1762 | No |
45 | ZAP70 | NA | ZAP70 Entrez,  Source | zeta-chain (TCR) associated protein kinase 70kDa | 16072 | -0.063 | -0.1781 | No |
46 | IL27 | NA | IL27 Entrez,  Source | interleukin 27 | 16712 | -0.090 | -0.2001 | No |
47 | NFAM1 | NA | NFAM1 Entrez,  Source | NFAT activating protein with ITAM motif 1 | 16832 | -0.094 | -0.2030 | No |
48 | ACVR1B | NA | ACVR1B Entrez,  Source | activin A receptor, type IB | 17427 | -0.121 | -0.2228 | No |
49 | IL10 | NA | IL10 Entrez,  Source | interleukin 10 | 17510 | -0.125 | -0.2238 | No |
50 | PRL | NA | PRL Entrez,  Source | prolactin | 18243 | -0.168 | -0.2480 | No |
51 | MAP4K1 | NA | MAP4K1 Entrez,  Source | mitogen-activated protein kinase kinase kinase kinase 1 | 18558 | -0.189 | -0.2565 | No |
52 | HCLS1 | NA | HCLS1 Entrez,  Source | hematopoietic cell-specific Lyn substrate 1 | 18598 | -0.193 | -0.2548 | No |
53 | ALAS2 | NA | ALAS2 Entrez,  Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 18816 | -0.211 | -0.2594 | No |
54 | LCK | NA | LCK Entrez,  Source | lymphocyte-specific protein tyrosine kinase | 19426 | -0.263 | -0.2775 | No |
55 | HDAC7 | NA | 19453 | -0.265 | -0.2742 | No | ||
56 | ACIN1 | NA | ACIN1 Entrez,  Source | apoptotic chromatin condensation inducer 1 | 20628 | -0.396 | -0.3109 | No |
57 | RPS19 | NA | RPS19 Entrez,  Source | ribosomal protein S19 | 20905 | -0.438 | -0.3140 | No |
58 | NHEJ1 | NA | NHEJ1 Entrez,  Source | nonhomologous end-joining factor 1 | 21740 | -0.579 | -0.3353 | No |
59 | RAB3D | NA | RAB3D Entrez,  Source | RAB3D, member RAS oncogene family | 22371 | -0.700 | -0.3472 | No |
60 | MLF1 | NA | MLF1 Entrez,  Source | myeloid leukemia factor 1 | 23877 | -1.059 | -0.3854 | Yes |
61 | IL31RA | NA | IL31RA Entrez,  Source | interleukin 31 receptor A | 24163 | -1.138 | -0.3775 | Yes |
62 | ETS1 | NA | ETS1 Entrez,  Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 24224 | -1.157 | -0.3612 | Yes |
63 | CEBPG | NA | CEBPG Entrez,  Source | CCAAT/enhancer binding protein (C/EBP), gamma | 24481 | -1.238 | -0.3507 | Yes |
64 | TGFB1 | NA | TGFB1 Entrez,  Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 24608 | -1.278 | -0.3348 | Yes |
65 | JAG2 | NA | JAG2 Entrez,  Source | jagged 2 | 25070 | -1.447 | -0.3284 | Yes |
66 | MMP9 | NA | MMP9 Entrez,  Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 25971 | -1.898 | -0.3310 | Yes |
67 | TPD52 | NA | TPD52 Entrez,  Source | tumor protein D52 | 26053 | -1.952 | -0.3026 | Yes |
68 | MYH9 | NA | MYH9 Entrez,  Source | myosin, heavy chain 9, non-muscle | 26135 | -2.006 | -0.2734 | Yes |
69 | SOCS5 | NA | SOCS5 Entrez,  Source | suppressor of cytokine signaling 5 | 26188 | -2.049 | -0.2424 | Yes |
70 | IFI16 | NA | IFI16 Entrez,  Source | interferon, gamma-inducible protein 16 | 26475 | -2.276 | -0.2163 | Yes |
71 | MAP4K2 | NA | MAP4K2 Entrez,  Source | mitogen-activated protein kinase kinase kinase kinase 2 | 26664 | -2.459 | -0.1837 | Yes |
72 | DYRK3 | NA | DYRK3 Entrez,  Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 26772 | -2.601 | -0.1459 | Yes |
73 | IL7 | NA | IL7 Entrez,  Source | interleukin 7 | 26962 | -2.930 | -0.1057 | Yes |
74 | LYN | NA | LYN Entrez,  Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 27040 | -3.155 | -0.0579 | Yes |
75 | TBX1 | NA | TBX1 Entrez,  Source | T-box 1 | 27264 | -4.262 | 0.0024 | Yes |