Datasetexpression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls
#wt_versus_radiation.mainSample.cls
#wt_versus_radiation_repos
PhenotypemainSample.cls#wt_versus_radiation_repos
Upregulated in class2
GeneSetHEMOPOIETIC_OR_LYMPHOID_ORGAN_DEVELOPMENT
Enrichment Score (ES)-0.4023755
Normalized Enrichment Score (NES)-1.5560699
Nominal p-value0.01268499
FDR q-value0.16536614
FWER p-Value0.656
Table: GSEA Results Summary



Fig 1: Enrichment plot: HEMOPOIETIC_OR_LYMPHOID_ORGAN_DEVELOPMENT   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1HDAC5NAHDAC5
Entrez,  Source
histone deacetylase 56202.6530.0199No
2CDK6NACDK6
Entrez,  Source
cyclin-dependent kinase 67742.4960.0543No
3RAG1NARAG1
Entrez,  Source
recombination activating gene 18422.4400.0911No
4NOTCH4NANOTCH4
Entrez,  Source
Notch homolog 4 (Drosophila)8772.4080.1285No
5ZBTB16NAZBTB16
Entrez,  Source
zinc finger and BTB domain containing 1612362.1420.1498No
6NOTCH2NANOTCH2
Entrez,  Source
Notch homolog 2 (Drosophila)29091.3460.1100No
7NCOA6NANCOA6
Entrez,  Source
nuclear receptor coactivator 634511.1680.1090No
8RUNX1NARUNX1
Entrez,  Source
runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)37161.0780.1166No
9ZNF675NAZNF675
Entrez,  Source
zinc finger protein 67540700.9670.1192No
10TGFB2NATGFB2
Entrez,  Source
transforming growth factor, beta 244140.8800.1207No
11KIRREL3NAKIRREL3
Entrez,  Source
kin of IRRE like 3 (Drosophila)45860.8430.1280No
12MAFBNAMAFB
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)51150.7160.1201No
13CD3DNACD3D
Entrez,  Source
CD3d molecule, delta (CD3-TCR complex)55350.6100.1145No
14LDB1NALDB1
Entrez,  Source
LIM domain binding 163040.4810.0941No
15CDC42NACDC42
Entrez,  Source
cell division cycle 42 (GTP binding protein, 25kDa)63150.4790.1014No
16ACVR2ANAACVR2A
Entrez,  Source
activin A receptor, type IIA63300.4760.1085No
17CSF1NACSF1
Entrez,  Source
colony stimulating factor 1 (macrophage)68520.4120.0960No
18MLLNAMLL
Entrez,  Source
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)74250.3510.0807No
19CD79ANACD79A
Entrez,  Source
CD79a molecule, immunoglobulin-associated alpha77090.3250.0755No
20LRMPNALRMP
Entrez,  Source
lymphoid-restricted membrane protein80980.2920.0660No
21HDAC9NAHDAC9
Entrez,  Source
histone deacetylase 981620.2870.0683No
22IL2NAIL2
Entrez,  Source
interleukin 285750.2580.0573No
23FOXO3NA89560.2320.0471No
24MALNAMAL
Entrez,  Source
mal, T-cell differentiation protein89710.2320.0503No
25SCINNASCIN
Entrez,  Source
scinderin92440.2160.0438No
26INHANAINHA
Entrez,  Source
inhibin, alpha94610.2050.0392No
27SNRKNASNRK
Entrez,  Source
SNF related kinase99840.1790.0229No
28HDAC4NAHDAC4
Entrez,  Source
histone deacetylase 4101900.1700.0181No
29CD4NACD4
Entrez,  Source
CD4 molecule103910.1610.0134No
30TM7SF4NATM7SF4
Entrez,  Source
transmembrane 7 superfamily member 4106400.1500.0067No
31BLNKNABLNK
Entrez,  Source
B-cell linker110830.128-0.0075No
32INHBANAINHBA
Entrez,  Source
inhibin, beta A (activin A, activin AB alpha polypeptide)118140.097-0.0327No
33IL4NAIL4
Entrez,  Source
interleukin 4120030.090-0.0382No
34IL12BNAIL12B
Entrez,  Source
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)123290.078-0.0488No
35SPINK5NASPINK5
Entrez,  Source
serine peptidase inhibitor, Kazal type 5123310.078-0.0476No
36TAZNATAZ
Entrez,  Source
tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome)124680.072-0.0515No
37RASGRP4NARASGRP4
Entrez,  Source
RAS guanyl releasing protein 4133850.038-0.0845No
38SPI1NASPI1
Entrez,  Source
spleen focus forming virus (SFFV) proviral integration oncogene spi1138220.021-0.1001No
39CARTPTNACARTPT
Entrez,  Source
CART prepropeptide140670.012-0.1089No
40CALCANACALCA
Entrez,  Source
calcitonin/calcitonin-related polypeptide, alpha15001-0.021-0.1427No
41CD1DNACD1D
Entrez,  Source
CD1d molecule15044-0.023-0.1439No
42PF4NAPF4
Entrez,  Source
platelet factor 4 (chemokine (C-X-C motif) ligand 4)15523-0.042-0.1608No
43SART1NASART1
Entrez,  Source
squamous cell carcinoma antigen recognised by T cells15650-0.046-0.1647No
44PTPRCNAPTPRC
Entrez,  Source
protein tyrosine phosphatase, receptor type, C15992-0.059-0.1762No
45ZAP70NAZAP70
Entrez,  Source
zeta-chain (TCR) associated protein kinase 70kDa16072-0.063-0.1781No
46IL27NAIL27
Entrez,  Source
interleukin 2716712-0.090-0.2001No
47NFAM1NANFAM1
Entrez,  Source
NFAT activating protein with ITAM motif 116832-0.094-0.2030No
48ACVR1BNAACVR1B
Entrez,  Source
activin A receptor, type IB17427-0.121-0.2228No
49IL10NAIL10
Entrez,  Source
interleukin 1017510-0.125-0.2238No
50PRLNAPRL
Entrez,  Source
prolactin18243-0.168-0.2480No
51MAP4K1NAMAP4K1
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 118558-0.189-0.2565No
52HCLS1NAHCLS1
Entrez,  Source
hematopoietic cell-specific Lyn substrate 118598-0.193-0.2548No
53ALAS2NAALAS2
Entrez,  Source
aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia)18816-0.211-0.2594No
54LCKNALCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase19426-0.263-0.2775No
55HDAC7NA19453-0.265-0.2742No
56ACIN1NAACIN1
Entrez,  Source
apoptotic chromatin condensation inducer 120628-0.396-0.3109No
57RPS19NARPS19
Entrez,  Source
ribosomal protein S1920905-0.438-0.3140No
58NHEJ1NANHEJ1
Entrez,  Source
nonhomologous end-joining factor 121740-0.579-0.3353No
59RAB3DNARAB3D
Entrez,  Source
RAB3D, member RAS oncogene family22371-0.700-0.3472No
60MLF1NAMLF1
Entrez,  Source
myeloid leukemia factor 123877-1.059-0.3854Yes
61IL31RANAIL31RA
Entrez,  Source
interleukin 31 receptor A24163-1.138-0.3775Yes
62ETS1NAETS1
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)24224-1.157-0.3612Yes
63CEBPGNACEBPG
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), gamma24481-1.238-0.3507Yes
64TGFB1NATGFB1
Entrez,  Source
transforming growth factor, beta 1 (Camurati-Engelmann disease)24608-1.278-0.3348Yes
65JAG2NAJAG2
Entrez,  Source
jagged 225070-1.447-0.3284Yes
66MMP9NAMMP9
Entrez,  Source
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)25971-1.898-0.3310Yes
67TPD52NATPD52
Entrez,  Source
tumor protein D5226053-1.952-0.3026Yes
68MYH9NAMYH9
Entrez,  Source
myosin, heavy chain 9, non-muscle26135-2.006-0.2734Yes
69SOCS5NASOCS5
Entrez,  Source
suppressor of cytokine signaling 526188-2.049-0.2424Yes
70IFI16NAIFI16
Entrez,  Source
interferon, gamma-inducible protein 1626475-2.276-0.2163Yes
71MAP4K2NAMAP4K2
Entrez,  Source
mitogen-activated protein kinase kinase kinase kinase 226664-2.459-0.1837Yes
72DYRK3NADYRK3
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 326772-2.601-0.1459Yes
73IL7NAIL7
Entrez,  Source
interleukin 726962-2.930-0.1057Yes
74LYNNALYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog27040-3.155-0.0579Yes
75TBX1NATBX1
Entrez,  Source
T-box 127264-4.2620.0024Yes
Table: GSEA details [plain text format]



Fig 2: HEMOPOIETIC_OR_LYMPHOID_ORGAN_DEVELOPMENT   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: HEMOPOIETIC_OR_LYMPHOID_ORGAN_DEVELOPMENT: Random ES distribution   
Gene set null distribution of ES for HEMOPOIETIC_OR_LYMPHOID_ORGAN_DEVELOPMENT