Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | INNATE_IMMUNE_RESPONSE |
| Enrichment Score (ES) | 0.43696707 |
| Normalized Enrichment Score (NES) | 1.7825409 |
| Nominal p-value | 0.0038834952 |
| FDR q-value | 0.032517347 |
| FWER p-Value | 0.14 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CADM1 | NA | 317 | 3.053 | 0.2636 | Yes | ||
| 2 | COLEC12 | NA | COLEC12 Entrez, Source | collectin sub-family member 12 | 1102 | 2.242 | 0.4370 | Yes |
| 3 | SFTPD | NA | SFTPD Entrez, Source | surfactant, pulmonary-associated protein D | 8328 | 0.275 | 0.1972 | No |
| 4 | BCL10 | NA | BCL10 Entrez, Source | B-cell CLL/lymphoma 10 | 9651 | 0.195 | 0.1664 | No |
| 5 | MBL2 | NA | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 9779 | 0.189 | 0.1787 | No |
| 6 | DEFB118 | NA | DEFB118 Entrez, Source | defensin, beta 118 | 10185 | 0.171 | 0.1793 | No |
| 7 | TLR8 | NA | TLR8 Entrez, Source | toll-like receptor 8 | 10189 | 0.171 | 0.1946 | No |
| 8 | IFNK | NA | IFNK Entrez, Source | interferon, kappa | 11455 | 0.112 | 0.1583 | No |
| 9 | DEFB1 | NA | DEFB1 Entrez, Source | defensin, beta 1 | 12165 | 0.084 | 0.1399 | No |
| 10 | PYDC1 | NA | PYDC1 Entrez, Source | PYD (pyrin domain) containing 1 | 12254 | 0.081 | 0.1440 | No |
| 11 | IL12B | NA | IL12B Entrez, Source | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 12329 | 0.078 | 0.1483 | No |
| 12 | APOA4 | NA | APOA4 Entrez, Source | apolipoprotein A-IV | 13367 | 0.039 | 0.1138 | No |
| 13 | KRT1 | NA | KRT1 Entrez, Source | keratin 1 (epidermolytic hyperkeratosis) | 14206 | 0.008 | 0.0838 | No |
| 14 | CD1D | NA | CD1D Entrez, Source | CD1d molecule | 15044 | -0.023 | 0.0552 | No |
| 15 | CRTAM | NA | CRTAM Entrez, Source | cytotoxic and regulatory T cell molecule | 15421 | -0.038 | 0.0448 | No |
| 16 | DEFB127 | NA | DEFB127 Entrez, Source | defensin, beta 127 | 16492 | -0.081 | 0.0129 | No |
| 17 | NCR1 | NA | NCR1 Entrez, Source | natural cytotoxicity triggering receptor 1 | 17671 | -0.132 | -0.0183 | No |
| 18 | EREG | NA | EREG Entrez, Source | epiregulin | 19078 | -0.233 | -0.0488 | No |
| 19 | APOBEC3G | NA | APOBEC3G Entrez, Source | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 19256 | -0.248 | -0.0329 | No |
| 20 | IL12A | NA | IL12A Entrez, Source | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | 20579 | -0.390 | -0.0461 | No |
| 21 | APOBEC3F | NA | APOBEC3F Entrez, Source | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F | 23373 | -0.920 | -0.0655 | No |
| 22 | DMBT1 | NA | DMBT1 Entrez, Source | deleted in malignant brain tumors 1 | 24023 | -1.095 | 0.0095 | No |
| 23 | CEBPG | NA | CEBPG Entrez, Source | CCAAT/enhancer binding protein (C/EBP), gamma | 24481 | -1.238 | 0.1043 | No |
