Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | LEUKOCYTE_DIFFERENTIATION |
| Enrichment Score (ES) | -0.51273274 |
| Normalized Enrichment Score (NES) | -1.6718931 |
| Nominal p-value | 0.01010101 |
| FDR q-value | 0.17243117 |
| FWER p-Value | 0.346 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HDAC5 | NA | HDAC5 Entrez, Source | histone deacetylase 5 | 620 | 2.653 | 0.0757 | No |
| 2 | RUNX1 | NA | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 3716 | 1.078 | 0.0023 | No |
| 3 | ZNF675 | NA | ZNF675 Entrez, Source | zinc finger protein 675 | 4070 | 0.967 | 0.0253 | No |
| 4 | CD3D | NA | CD3D Entrez, Source | CD3d molecule, delta (CD3-TCR complex) | 5535 | 0.610 | -0.0057 | No |
| 5 | CDC42 | NA | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 6315 | 0.479 | -0.0165 | No |
| 6 | CSF1 | NA | CSF1 Entrez, Source | colony stimulating factor 1 (macrophage) | 6852 | 0.412 | -0.0208 | No |
| 7 | CD79A | NA | CD79A Entrez, Source | CD79a molecule, immunoglobulin-associated alpha | 7709 | 0.325 | -0.0401 | No |
| 8 | HDAC9 | NA | HDAC9 Entrez, Source | histone deacetylase 9 | 8162 | 0.287 | -0.0460 | No |
| 9 | IL2 | NA | IL2 Entrez, Source | interleukin 2 | 8575 | 0.258 | -0.0515 | No |
| 10 | INHA | NA | INHA Entrez, Source | inhibin, alpha | 9461 | 0.205 | -0.0763 | No |
| 11 | HDAC4 | NA | HDAC4 Entrez, Source | histone deacetylase 4 | 10190 | 0.170 | -0.0967 | No |
| 12 | CD4 | NA | CD4 Entrez, Source | CD4 molecule | 10391 | 0.161 | -0.0980 | No |
| 13 | TM7SF4 | NA | TM7SF4 Entrez, Source | transmembrane 7 superfamily member 4 | 10640 | 0.150 | -0.1016 | No |
| 14 | INHBA | NA | INHBA Entrez, Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 11814 | 0.097 | -0.1409 | No |
| 15 | IL4 | NA | IL4 Entrez, Source | interleukin 4 | 12003 | 0.090 | -0.1445 | No |
| 16 | IL12B | NA | IL12B Entrez, Source | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 12329 | 0.078 | -0.1535 | No |
| 17 | SPINK5 | NA | SPINK5 Entrez, Source | serine peptidase inhibitor, Kazal type 5 | 12331 | 0.078 | -0.1507 | No |
| 18 | CARTPT | NA | CARTPT Entrez, Source | CART prepropeptide | 14067 | 0.012 | -0.2138 | No |
| 19 | CALCA | NA | CALCA Entrez, Source | calcitonin/calcitonin-related polypeptide, alpha | 15001 | -0.021 | -0.2472 | No |
| 20 | CD1D | NA | CD1D Entrez, Source | CD1d molecule | 15044 | -0.023 | -0.2479 | No |
| 21 | SART1 | NA | SART1 Entrez, Source | squamous cell carcinoma antigen recognised by T cells | 15650 | -0.046 | -0.2683 | No |
| 22 | PTPRC | NA | PTPRC Entrez, Source | protein tyrosine phosphatase, receptor type, C | 15992 | -0.059 | -0.2786 | No |
| 23 | ZAP70 | NA | ZAP70 Entrez, Source | zeta-chain (TCR) associated protein kinase 70kDa | 16072 | -0.063 | -0.2792 | No |
| 24 | IL27 | NA | IL27 Entrez, Source | interleukin 27 | 16712 | -0.090 | -0.2992 | No |
| 25 | NFAM1 | NA | NFAM1 Entrez, Source | NFAT activating protein with ITAM motif 1 | 16832 | -0.094 | -0.3001 | No |
| 26 | LCK | NA | LCK Entrez, Source | lymphocyte-specific protein tyrosine kinase | 19426 | -0.263 | -0.3853 | No |
| 27 | HDAC7 | NA | 19453 | -0.265 | -0.3765 | No | ||
| 28 | ACIN1 | NA | ACIN1 Entrez, Source | apoptotic chromatin condensation inducer 1 | 20628 | -0.396 | -0.4048 | No |
| 29 | NHEJ1 | NA | NHEJ1 Entrez, Source | nonhomologous end-joining factor 1 | 21740 | -0.579 | -0.4240 | No |
| 30 | IL31RA | NA | IL31RA Entrez, Source | interleukin 31 receptor A | 24163 | -1.138 | -0.4705 | Yes |
| 31 | CEBPG | NA | CEBPG Entrez, Source | CCAAT/enhancer binding protein (C/EBP), gamma | 24481 | -1.238 | -0.4362 | Yes |
| 32 | JAG2 | NA | JAG2 Entrez, Source | jagged 2 | 25070 | -1.447 | -0.4040 | Yes |
| 33 | MMP9 | NA | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 25971 | -1.898 | -0.3665 | Yes |
| 34 | TPD52 | NA | TPD52 Entrez, Source | tumor protein D52 | 26053 | -1.952 | -0.2971 | Yes |
| 35 | MYH9 | NA | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 26135 | -2.006 | -0.2256 | Yes |
| 36 | SOCS5 | NA | SOCS5 Entrez, Source | suppressor of cytokine signaling 5 | 26188 | -2.049 | -0.1515 | Yes |
| 37 | IFI16 | NA | IFI16 Entrez, Source | interferon, gamma-inducible protein 16 | 26475 | -2.276 | -0.0775 | Yes |
| 38 | IL7 | NA | IL7 Entrez, Source | interleukin 7 | 26962 | -2.930 | 0.0134 | Yes |
