Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | LYMPHOCYTE_DIFFERENTIATION |
| Enrichment Score (ES) | -0.49267447 |
| Normalized Enrichment Score (NES) | -1.5649413 |
| Nominal p-value | 0.008130081 |
| FDR q-value | 0.17165104 |
| FWER p-Value | 0.628 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HDAC5 | NA | HDAC5 Entrez, Source | histone deacetylase 5 | 620 | 2.653 | 0.1420 | No |
| 2 | CD3D | NA | CD3D Entrez, Source | CD3d molecule, delta (CD3-TCR complex) | 5535 | 0.610 | -0.0001 | No |
| 3 | CD79A | NA | CD79A Entrez, Source | CD79a molecule, immunoglobulin-associated alpha | 7709 | 0.325 | -0.0596 | No |
| 4 | HDAC9 | NA | HDAC9 Entrez, Source | histone deacetylase 9 | 8162 | 0.287 | -0.0583 | No |
| 5 | IL2 | NA | IL2 Entrez, Source | interleukin 2 | 8575 | 0.258 | -0.0574 | No |
| 6 | INHA | NA | INHA Entrez, Source | inhibin, alpha | 9461 | 0.205 | -0.0770 | No |
| 7 | HDAC4 | NA | HDAC4 Entrez, Source | histone deacetylase 4 | 10190 | 0.170 | -0.0931 | No |
| 8 | CD4 | NA | CD4 Entrez, Source | CD4 molecule | 10391 | 0.161 | -0.0905 | No |
| 9 | INHBA | NA | INHBA Entrez, Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 11814 | 0.097 | -0.1365 | No |
| 10 | IL4 | NA | IL4 Entrez, Source | interleukin 4 | 12003 | 0.090 | -0.1378 | No |
| 11 | IL12B | NA | IL12B Entrez, Source | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 12329 | 0.078 | -0.1449 | No |
| 12 | SPINK5 | NA | SPINK5 Entrez, Source | serine peptidase inhibitor, Kazal type 5 | 12331 | 0.078 | -0.1401 | No |
| 13 | CD1D | NA | CD1D Entrez, Source | CD1d molecule | 15044 | -0.023 | -0.2380 | No |
| 14 | SART1 | NA | SART1 Entrez, Source | squamous cell carcinoma antigen recognised by T cells | 15650 | -0.046 | -0.2573 | No |
| 15 | PTPRC | NA | PTPRC Entrez, Source | protein tyrosine phosphatase, receptor type, C | 15992 | -0.059 | -0.2661 | No |
| 16 | ZAP70 | NA | ZAP70 Entrez, Source | zeta-chain (TCR) associated protein kinase 70kDa | 16072 | -0.063 | -0.2651 | No |
| 17 | IL27 | NA | IL27 Entrez, Source | interleukin 27 | 16712 | -0.090 | -0.2829 | No |
| 18 | NFAM1 | NA | NFAM1 Entrez, Source | NFAT activating protein with ITAM motif 1 | 16832 | -0.094 | -0.2814 | No |
| 19 | LCK | NA | LCK Entrez, Source | lymphocyte-specific protein tyrosine kinase | 19426 | -0.263 | -0.3601 | No |
| 20 | HDAC7 | NA | 19453 | -0.265 | -0.3445 | No | ||
| 21 | NHEJ1 | NA | NHEJ1 Entrez, Source | nonhomologous end-joining factor 1 | 21740 | -0.579 | -0.3923 | No |
| 22 | CEBPG | NA | CEBPG Entrez, Source | CCAAT/enhancer binding protein (C/EBP), gamma | 24481 | -1.238 | -0.4159 | Yes |
| 23 | JAG2 | NA | JAG2 Entrez, Source | jagged 2 | 25070 | -1.447 | -0.3475 | Yes |
| 24 | TPD52 | NA | TPD52 Entrez, Source | tumor protein D52 | 26053 | -1.952 | -0.2624 | Yes |
| 25 | SOCS5 | NA | SOCS5 Entrez, Source | suppressor of cytokine signaling 5 | 26188 | -2.049 | -0.1401 | Yes |
| 26 | IL7 | NA | IL7 Entrez, Source | interleukin 7 | 26962 | -2.930 | 0.0134 | Yes |
