Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | MACROMOLECULAR_COMPLEX_DISASSEMBLY |
| Enrichment Score (ES) | -0.59341395 |
| Normalized Enrichment Score (NES) | -1.8210125 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07319165 |
| FWER p-Value | 0.108 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SMARCE1 | NA | SMARCE1 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | 1783 | 1.834 | 0.0370 | No |
| 2 | NRG1 | NA | NRG1 Entrez, Source | neuregulin 1 | 3117 | 1.271 | 0.0591 | No |
| 3 | MTRF1 | NA | MTRF1 Entrez, Source | mitochondrial translational release factor 1 | 3709 | 1.080 | 0.0977 | No |
| 4 | SET | NA | SET Entrez, Source | SET translocation (myeloid leukemia-associated) | 4091 | 0.961 | 0.1374 | No |
| 5 | TNP1 | NA | TNP1 Entrez, Source | transition protein 1 (during histone to protamine replacement) | 6288 | 0.483 | 0.0840 | No |
| 6 | IRAK3 | NA | IRAK3 Entrez, Source | interleukin-1 receptor-associated kinase 3 | 13477 | 0.034 | -0.1773 | No |
| 7 | SUPT16H | NA | SUPT16H Entrez, Source | suppressor of Ty 16 homolog (S. cerevisiae) | 14514 | -0.003 | -0.2150 | No |
| 8 | MTIF3 | NA | MTIF3 Entrez, Source | - | 18359 | -0.176 | -0.3460 | No |
| 9 | UPF1 | NA | UPF1 Entrez, Source | UPF1 regulator of nonsense transcripts homolog (yeast) | 19842 | -0.304 | -0.3833 | No |
| 10 | MTERF | NA | MTERF Entrez, Source | mitochondrial transcription termination factor | 25583 | -1.680 | -0.4997 | Yes |
| 11 | MAZ | NA | MAZ Entrez, Source | MYC-associated zinc finger protein (purine-binding transcription factor) | 25753 | -1.770 | -0.4072 | Yes |
| 12 | ETF1 | NA | ETF1 Entrez, Source | eukaryotic translation termination factor 1 | 25755 | -1.770 | -0.3084 | Yes |
| 13 | HMGA1 | NA | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 25760 | -1.774 | -0.2096 | Yes |
| 14 | HRSP12 | NA | HRSP12 Entrez, Source | heat-responsive protein 12 | 25987 | -1.909 | -0.1114 | Yes |
| 15 | TTF2 | NA | TTF2 Entrez, Source | transcription termination factor, RNA polymerase II | 26932 | -2.877 | 0.0145 | Yes |
