Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | PROTEIN_POLYMERIZATION |
| Enrichment Score (ES) | 0.57812047 |
| Normalized Enrichment Score (NES) | 1.6481134 |
| Nominal p-value | 0.004484305 |
| FDR q-value | 0.07210142 |
| FWER p-Value | 0.418 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MAPT | NA | MAPT Entrez, Source | microtubule-associated protein tau | 96 | 3.498 | 0.1548 | Yes |
| 2 | NCK2 | NA | NCK2 Entrez, Source | NCK adaptor protein 2 | 415 | 2.906 | 0.2747 | Yes |
| 3 | PREX1 | NA | PREX1 Entrez, Source | - | 499 | 2.796 | 0.3982 | Yes |
| 4 | RAC1 | NA | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 869 | 2.415 | 0.4940 | Yes |
| 5 | GSN | NA | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 1877 | 1.789 | 0.5381 | Yes |
| 6 | CDC42EP5 | NA | CDC42EP5 Entrez, Source | CDC42 effector protein (Rho GTPase binding) 5 | 3136 | 1.262 | 0.5491 | Yes |
| 7 | WASF3 | NA | WASF3 Entrez, Source | WAS protein family, member 3 | 3687 | 1.086 | 0.5781 | Yes |
| 8 | NCK1 | NA | NCK1 Entrez, Source | NCK adaptor protein 1 | 6863 | 0.412 | 0.4805 | No |
| 9 | ARF6 | NA | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 13142 | 0.047 | 0.2528 | No |
| 10 | TMSB4Y | NA | TMSB4Y Entrez, Source | thymosin, beta 4, Y-linked | 16657 | -0.087 | 0.1280 | No |
| 11 | SPRR2C | NA | SPRR2C Entrez, Source | small proline-rich protein 2C | 17290 | -0.114 | 0.1101 | No |
| 12 | LATS1 | NA | LATS1 Entrez, Source | LATS, large tumor suppressor, homolog 1 (Drosophila) | 19021 | -0.229 | 0.0571 | No |
| 13 | MAPRE1 | NA | MAPRE1 Entrez, Source | microtubule-associated protein, RP/EB family, member 1 | 20611 | -0.394 | 0.0167 | No |
| 14 | TPPP | NA | TPPP Entrez, Source | - | 20691 | -0.405 | 0.0321 | No |
| 15 | RASA1 | NA | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 21094 | -0.467 | 0.0385 | No |
| 16 | ANG | NA | ANG Entrez, Source | angiogenin, ribonuclease, RNase A family, 5 | 21162 | -0.475 | 0.0576 | No |
| 17 | CENPJ | NA | CENPJ Entrez, Source | centromere protein J | 24000 | -1.090 | 0.0030 | No |
| 18 | CDC42EP2 | NA | CDC42EP2 Entrez, Source | CDC42 effector protein (Rho GTPase binding) 2 | 24413 | -1.214 | 0.0429 | No |
| 19 | WASF1 | NA | WASF1 Entrez, Source | WAS protein family, member 1 | 24984 | -1.411 | 0.0859 | No |
