Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | REGULATION_OF_ACTION_POTENTIAL |
| Enrichment Score (ES) | 0.47302333 |
| Normalized Enrichment Score (NES) | 1.6286783 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.071952164 |
| FWER p-Value | 0.474 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | KCND2 | NA | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 69 | 3.574 | 0.1268 | Yes |
| 2 | SRI | NA | SRI Entrez, Source | sorcin | 99 | 3.489 | 0.2519 | Yes |
| 3 | CD9 | NA | CD9 Entrez, Source | CD9 molecule | 156 | 3.343 | 0.3707 | Yes |
| 4 | PLP1 | NA | PLP1 Entrez, Source | proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) | 339 | 3.012 | 0.4730 | Yes |
| 5 | SOD1 | NA | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 3584 | 1.126 | 0.3950 | No |
| 6 | AMIGO1 | NA | AMIGO1 Entrez, Source | adhesion molecule with Ig-like domain 1 | 5849 | 0.553 | 0.3321 | No |
| 7 | EIF2B5 | NA | EIF2B5 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa | 7500 | 0.344 | 0.2841 | No |
| 8 | MAL | NA | MAL Entrez, Source | mal, T-cell differentiation protein | 8971 | 0.232 | 0.2387 | No |
| 9 | EIF2B2 | NA | EIF2B2 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa | 14251 | 0.006 | 0.0456 | No |
| 10 | KCNMB2 | NA | KCNMB2 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 2 | 15886 | -0.055 | -0.0122 | No |
| 11 | KLK8 | NA | KLK8 Entrez, Source | kallikrein 8 (neuropsin/ovasin) | 22369 | -0.699 | -0.2242 | No |
| 12 | EIF2B4 | NA | EIF2B4 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | 22651 | -0.765 | -0.2069 | No |
| 13 | PPARD | NA | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 23875 | -1.058 | -0.2133 | No |
| 14 | KCNMB4 | NA | KCNMB4 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 4 | 25047 | -1.437 | -0.2042 | No |
| 15 | NF1 | NA | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 25328 | -1.560 | -0.1581 | No |
| 16 | KCNMB3 | NA | KCNMB3 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M beta member 3 | 26349 | -2.172 | -0.1169 | No |
| 17 | MBP | NA | MBP Entrez, Source | myelin basic protein | 27258 | -4.222 | 0.0026 | No |
