Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | REGULATION_OF_BLOOD_PRESSURE |
| Enrichment Score (ES) | 0.6832776 |
| Normalized Enrichment Score (NES) | 1.8210679 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.027579462 |
| FWER p-Value | 0.098 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | NPR2 | NA | NPR2 Entrez, Source | natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) | 2221 | 1.625 | 0.0594 | Yes |
| 2 | NPPA | NA | NPPA Entrez, Source | natriuretic peptide precursor A | 2392 | 1.551 | 0.1875 | Yes |
| 3 | AGT | NA | AGT Entrez, Source | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 2542 | 1.486 | 0.3107 | Yes |
| 4 | PTGS1 | NA | PTGS1 Entrez, Source | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 2791 | 1.388 | 0.4218 | Yes |
| 5 | RENBP | NA | RENBP Entrez, Source | renin binding protein | 3299 | 1.215 | 0.5084 | Yes |
| 6 | SOD1 | NA | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 3584 | 1.126 | 0.5955 | Yes |
| 7 | ATP6AP2 | NA | ATP6AP2 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 2 | 3727 | 1.074 | 0.6833 | Yes |
| 8 | ERAP2 | NA | 8182 | 0.286 | 0.5449 | No | ||
| 9 | PTGS2 | NA | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 9159 | 0.221 | 0.5283 | No |
| 10 | CYP11B2 | NA | CYP11B2 Entrez, Source | cytochrome P450, family 11, subfamily B, polypeptide 2 | 10221 | 0.169 | 0.5041 | No |
| 11 | CORIN | NA | CORIN Entrez, Source | corin, serine peptidase | 12517 | 0.070 | 0.4262 | No |
| 12 | AGTR2 | NA | AGTR2 Entrez, Source | angiotensin II receptor, type 2 | 12540 | 0.070 | 0.4314 | No |
| 13 | CARTPT | NA | CARTPT Entrez, Source | CART prepropeptide | 14067 | 0.012 | 0.3766 | No |
| 14 | GNB3 | NA | GNB3 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 3 | 14253 | 0.006 | 0.3703 | No |
| 15 | ACE | NA | ACE Entrez, Source | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 14808 | -0.013 | 0.3512 | No |
| 16 | CALCA | NA | CALCA Entrez, Source | calcitonin/calcitonin-related polypeptide, alpha | 15001 | -0.021 | 0.3460 | No |
| 17 | ACVRL1 | NA | ACVRL1 Entrez, Source | activin A receptor type II-like 1 | 16175 | -0.068 | 0.3089 | No |
| 18 | UTS2 | NA | UTS2 Entrez, Source | urotensin 2 | 16701 | -0.089 | 0.2974 | No |
| 19 | BRS3 | NA | BRS3 Entrez, Source | bombesin-like receptor 3 | 18043 | -0.155 | 0.2618 | No |
| 20 | GCGR | NA | GCGR Entrez, Source | glucagon receptor | 19329 | -0.253 | 0.2366 | No |
| 21 | CHGA | NA | CHGA Entrez, Source | chromogranin A (parathyroid secretory protein 1) | 19395 | -0.260 | 0.2568 | No |
| 22 | REN | NA | REN Entrez, Source | renin | 20573 | -0.390 | 0.2474 | No |
