Datasetexpression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls
#wt_versus_radiation.mainSample.cls
#wt_versus_radiation_repos
PhenotypemainSample.cls#wt_versus_radiation_repos
Upregulated in class2
GeneSetREGULATION_OF_NEUROTRANSMITTER_LEVELS
Enrichment Score (ES)-0.5079024
Normalized Enrichment Score (NES)-1.6307356
Nominal p-value0.0038986355
FDR q-value0.1659067
FWER p-Value0.454
Table: GSEA Results Summary



Fig 1: Enrichment plot: REGULATION_OF_NEUROTRANSMITTER_LEVELS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1NLGN1NANLGN1
Entrez,  Source
neuroligin 15742.6940.0879No
2SLC1A3NASLC1A3
Entrez,  Source
solute carrier family 1 (glial high affinity glutamate transporter), member 316071.9210.1278No
3SNCAIPNASNCAIP
Entrez,  Source
synuclein, alpha interacting protein (synphilin)31981.2410.1198No
4RAB3ANARAB3A
Entrez,  Source
RAB3A, member RAS oncogene family40880.9620.1262No
5TGFB2NATGFB2
Entrez,  Source
transforming growth factor, beta 244140.8800.1499No
6SNAPINNA59950.5270.1133No
7SYN3NASYN3
Entrez,  Source
synapsin III70430.3920.0908No
8COLQNACOLQ
Entrez,  Source
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase72240.3730.0993No
9RIMS1NARIMS1
Entrez,  Source
regulating synaptic membrane exocytosis 190200.2290.0428No
10CARTPTNACARTPT
Entrez,  Source
CART prepropeptide140670.012-0.1415No
11GDNFNAGDNF
Entrez,  Source
glial cell derived neurotrophic factor14707-0.010-0.1645No
12BAIAP3NABAIAP3
Entrez,  Source
BAI1-associated protein 314998-0.021-0.1742No
13HRH3NAHRH3
Entrez,  Source
histamine receptor H315171-0.028-0.1794No
14SLC5A7NASLC5A7
Entrez,  Source
solute carrier family 5 (choline transporter), member 715806-0.052-0.2005No
15SLC6A4NASLC6A4
Entrez,  Source
solute carrier family 6 (neurotransmitter transporter, serotonin), member 417580-0.128-0.2602No
16PRG3NAPRG3
Entrez,  Source
proteoglycan 319742-0.294-0.3275No
17GRM4NAGRM4
Entrez,  Source
glutamate receptor, metabotropic 420203-0.342-0.3305No
18KCNMB4NAKCNMB4
Entrez,  Source
potassium large conductance calcium-activated channel, subfamily M, beta member 425047-1.437-0.4498Yes
19SYT1NASYT1
Entrez,  Source
synaptotagmin I26109-1.987-0.4083Yes
20ALDH9A1NAALDH9A1
Entrez,  Source
aldehyde dehydrogenase 9 family, member A126263-2.096-0.3291Yes
21HPRT1NAHPRT1
Entrez,  Source
hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)26770-2.597-0.2426Yes
22GCH1NAGCH1
Entrez,  Source
GTP cyclohydrolase 1 (dopa-responsive dystonia)26961-2.929-0.1311Yes
23GCHFRNAGCHFR
Entrez,  Source
GTP cyclohydrolase I feedback regulator27159-3.5740.0062Yes
Table: GSEA details [plain text format]



Fig 2: REGULATION_OF_NEUROTRANSMITTER_LEVELS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: REGULATION_OF_NEUROTRANSMITTER_LEVELS: Random ES distribution   
Gene set null distribution of ES for REGULATION_OF_NEUROTRANSMITTER_LEVELS