Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | RESPONSE_TO_HORMONE_STIMULUS |
| Enrichment Score (ES) | -0.5621516 |
| Normalized Enrichment Score (NES) | -1.5858543 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.20969135 |
| FWER p-Value | 0.576 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | NCOA6 | NA | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 3451 | 1.168 | -0.0874 | No |
| 2 | TSC1 | NA | TSC1 Entrez, Source | tuberous sclerosis 1 | 4433 | 0.875 | -0.0942 | No |
| 3 | ADIPOR1 | NA | ADIPOR1 Entrez, Source | adiponectin receptor 1 | 4530 | 0.855 | -0.0692 | No |
| 4 | CRIPAK | NA | CRIPAK Entrez, Source | cysteine-rich PAK1 inhibitor | 4975 | 0.748 | -0.0605 | No |
| 5 | EIF2B1 | NA | EIF2B1 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | 5507 | 0.616 | -0.0593 | No |
| 6 | EIF2B5 | NA | EIF2B5 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa | 7500 | 0.344 | -0.1208 | No |
| 7 | ADIPOR2 | NA | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 12241 | 0.081 | -0.2918 | No |
| 8 | ABCA2 | NA | ABCA2 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 2 | 12571 | 0.069 | -0.3015 | No |
| 9 | GHRL | NA | GHRL Entrez, Source | ghrelin/obestatin preprohormone | 14071 | 0.012 | -0.3560 | No |
| 10 | EIF2B2 | NA | EIF2B2 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa | 14251 | 0.006 | -0.3624 | No |
| 11 | CALCR | NA | CALCR Entrez, Source | calcitonin receptor | 15077 | -0.024 | -0.3918 | No |
| 12 | RBM14 | NA | RBM14 Entrez, Source | RNA binding motif protein 14 | 16901 | -0.097 | -0.4554 | No |
| 13 | BRCA2 | NA | BRCA2 Entrez, Source | breast cancer 2, early onset | 17741 | -0.137 | -0.4815 | No |
| 14 | HCLS1 | NA | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 18598 | -0.193 | -0.5064 | No |
| 15 | LATS1 | NA | LATS1 Entrez, Source | LATS, large tumor suppressor, homolog 1 (Drosophila) | 19021 | -0.229 | -0.5143 | No |
| 16 | GHSR | NA | GHSR Entrez, Source | growth hormone secretagogue receptor | 19478 | -0.268 | -0.5220 | No |
| 17 | GSTM3 | NA | GSTM3 Entrez, Source | glutathione S-transferase M3 (brain) | 20083 | -0.329 | -0.5332 | No |
| 18 | KRT19 | NA | KRT19 Entrez, Source | keratin 19 | 20314 | -0.357 | -0.5296 | No |
| 19 | ANG | NA | ANG Entrez, Source | angiogenin, ribonuclease, RNase A family, 5 | 21162 | -0.475 | -0.5448 | Yes |
| 20 | FOXC2 | NA | FOXC2 Entrez, Source | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 21636 | -0.557 | -0.5436 | Yes |
| 21 | PDCD7 | NA | PDCD7 Entrez, Source | programmed cell death 7 | 21753 | -0.582 | -0.5284 | Yes |
| 22 | BRCA1 | NA | BRCA1 Entrez, Source | breast cancer 1, early onset | 22114 | -0.650 | -0.5199 | Yes |
| 23 | PCSK9 | NA | PCSK9 Entrez, Source | proprotein convertase subtilisin/kexin type 9 | 22427 | -0.713 | -0.5075 | Yes |
| 24 | EIF2B4 | NA | EIF2B4 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | 22651 | -0.765 | -0.4901 | Yes |
| 25 | LATS2 | NA | LATS2 Entrez, Source | LATS, large tumor suppressor, homolog 2 (Drosophila) | 23795 | -1.034 | -0.4975 | Yes |
| 26 | EIF2B3 | NA | EIF2B3 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa | 24097 | -1.117 | -0.4712 | Yes |
| 27 | CD24 | NA | CD24 Entrez, Source | CD24 molecule | 24149 | -1.134 | -0.4352 | Yes |
| 28 | GCLC | NA | GCLC Entrez, Source | glutamate-cysteine ligase, catalytic subunit | 26243 | -2.083 | -0.4424 | Yes |
| 29 | ME1 | NA | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 26454 | -2.261 | -0.3746 | Yes |
| 30 | GATA3 | NA | GATA3 Entrez, Source | GATA binding protein 3 | 26652 | -2.449 | -0.3001 | Yes |
| 31 | LYN | NA | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 27040 | -3.155 | -0.2090 | Yes |
| 32 | RERG | NA | RERG Entrez, Source | RAS-like, estrogen-regulated, growth inhibitor | 27069 | -3.233 | -0.1021 | Yes |
| 33 | STEAP2 | NA | STEAP2 Entrez, Source | six transmembrane epithelial antigen of the prostate 2 | 27097 | -3.343 | 0.0085 | Yes |
