Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | RNA_CATABOLIC_PROCESS |
| Enrichment Score (ES) | -0.6366116 |
| Normalized Enrichment Score (NES) | -1.5571668 |
| Nominal p-value | 0.008421052 |
| FDR q-value | 0.1744159 |
| FWER p-Value | 0.653 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SMG6 | NA | SMG6 Entrez, Source | Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) | 2944 | 1.332 | -0.0597 | No |
| 2 | HNRNPD | NA | 5039 | 0.735 | -0.1099 | No | ||
| 3 | RNASE6 | NA | RNASE6 Entrez, Source | ribonuclease, RNase A family, k6 | 5248 | 0.678 | -0.0930 | No |
| 4 | PPP1R8 | NA | PPP1R8 Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 8 | 5947 | 0.539 | -0.0992 | No |
| 5 | RNASE2 | NA | RNASE2 Entrez, Source | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 6759 | 0.423 | -0.1136 | No |
| 6 | RNASE3 | NA | RNASE3 Entrez, Source | ribonuclease, RNase A family, 3 (eosinophil cationic protein) | 11558 | 0.108 | -0.2854 | No |
| 7 | RNASEH2A | NA | RNASEH2A Entrez, Source | ribonuclease H2, subunit A | 14013 | 0.015 | -0.3747 | No |
| 8 | ERN2 | NA | ERN2 Entrez, Source | endoplasmic reticulum to nucleus signalling 2 | 17023 | -0.102 | -0.4813 | No |
| 9 | SMG5 | NA | SMG5 Entrez, Source | Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) | 20236 | -0.346 | -0.5864 | No |
| 10 | SMG1 | NA | SMG1 Entrez, Source | - | 20351 | -0.363 | -0.5775 | No |
| 11 | UPF2 | NA | UPF2 Entrez, Source | UPF2 regulator of nonsense transcripts homolog (yeast) | 21200 | -0.481 | -0.5912 | No |
| 12 | PABPC4 | NA | PABPC4 Entrez, Source | poly(A) binding protein, cytoplasmic 4 (inducible form) | 22441 | -0.715 | -0.6108 | Yes |
| 13 | AUH | NA | AUH Entrez, Source | AU RNA binding protein/enoyl-Coenzyme A hydratase | 23110 | -0.860 | -0.6042 | Yes |
| 14 | ZFP36 | NA | ZFP36 Entrez, Source | zinc finger protein 36, C3H type, homolog (mouse) | 23258 | -0.893 | -0.5774 | Yes |
| 15 | XRN2 | NA | XRN2 Entrez, Source | 5'-3' exoribonuclease 2 | 23446 | -0.937 | -0.5504 | Yes |
| 16 | GSPT1 | NA | GSPT1 Entrez, Source | G1 to S phase transition 1 | 24955 | -1.399 | -0.5552 | Yes |
| 17 | HSPA1B | NA | HSPA1B Entrez, Source | heat shock 70kDa protein 1B | 26174 | -2.044 | -0.5260 | Yes |
| 18 | SMG7 | NA | SMG7 Entrez, Source | Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) | 26223 | -2.074 | -0.4529 | Yes |
| 19 | POP1 | NA | POP1 Entrez, Source | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) | 26556 | -2.348 | -0.3804 | Yes |
| 20 | RNASET2 | NA | RNASET2 Entrez, Source | ribonuclease T2 | 26581 | -2.368 | -0.2958 | Yes |
| 21 | RNASEH1 | NA | RNASEH1 Entrez, Source | ribonuclease H1 | 26878 | -2.780 | -0.2063 | Yes |
| 22 | ABCE1 | NA | ABCE1 Entrez, Source | ATP-binding cassette, sub-family E (OABP), member 1 | 26921 | -2.856 | -0.1048 | Yes |
| 23 | ISG20 | NA | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 27089 | -3.317 | 0.0088 | Yes |
