Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | TUBE_DEVELOPMENT |
| Enrichment Score (ES) | 0.610032 |
| Normalized Enrichment Score (NES) | 1.6807352 |
| Nominal p-value | 0.0020876827 |
| FDR q-value | 0.06280864 |
| FWER p-Value | 0.342 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LMO4 | NA | LMO4 Entrez, Source | LIM domain only 4 | 291 | 3.100 | 0.1529 | Yes |
| 2 | VANGL2 | NA | VANGL2 Entrez, Source | vang-like 2 (van gogh, Drosophila) | 553 | 2.710 | 0.2864 | Yes |
| 3 | PDPN | NA | PDPN Entrez, Source | podoplanin | 598 | 2.678 | 0.4261 | Yes |
| 4 | NOTCH4 | NA | NOTCH4 Entrez, Source | Notch homolog 4 (Drosophila) | 877 | 2.408 | 0.5429 | Yes |
| 5 | GLI2 | NA | GLI2 Entrez, Source | GLI-Kruppel family member GLI2 | 3079 | 1.284 | 0.5301 | Yes |
| 6 | SOD1 | NA | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 3584 | 1.126 | 0.5711 | Yes |
| 7 | CELSR1 | NA | CELSR1 Entrez, Source | cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) | 3960 | 0.998 | 0.6100 | Yes |
| 8 | SFTPD | NA | SFTPD Entrez, Source | surfactant, pulmonary-associated protein D | 8328 | 0.275 | 0.4647 | No |
| 9 | SHH | NA | SHH Entrez, Source | sonic hedgehog homolog (Drosophila) | 9147 | 0.222 | 0.4464 | No |
| 10 | NKX2-6 | NA | NKX2-6 Entrez, Source | NK2 transcription factor related, locus 6 (Drosophila) | 9292 | 0.214 | 0.4524 | No |
| 11 | BCL10 | NA | BCL10 Entrez, Source | B-cell CLL/lymphoma 10 | 9651 | 0.195 | 0.4496 | No |
| 12 | KEL | NA | KEL Entrez, Source | Kell blood group, metallo-endopeptidase | 14298 | 0.004 | 0.2797 | No |
| 13 | GCLM | NA | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 14683 | -0.009 | 0.2661 | No |
| 14 | CALCA | NA | CALCA Entrez, Source | calcitonin/calcitonin-related polypeptide, alpha | 15001 | -0.021 | 0.2556 | No |
| 15 | KCNMB2 | NA | KCNMB2 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 2 | 15886 | -0.055 | 0.2262 | No |
| 16 | TINAG | NA | TINAG Entrez, Source | tubulointerstitial nephritis antigen | 17657 | -0.132 | 0.1683 | No |
| 17 | KCNMB4 | NA | KCNMB4 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 4 | 25047 | -1.437 | -0.0264 | No |
| 18 | GCLC | NA | GCLC Entrez, Source | glutamate-cysteine ligase, catalytic subunit | 26243 | -2.083 | 0.0398 | No |
